ArticlePediatrics2023
Diagnostic Accuracy of Primary Care Clinicians Across a Statewide System of Autism Evaluation.
Article in Pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The Diagnostic Potential of Eye Tracking to Detect Autism Spectrum Disorder in Children: A Systematic Review.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Building Capacity: A Systematic Review of Training in the Diagnosis of Autism for Community-Based Clinicians.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- Failure points in the early autism identification pathway for children aged 0-5 years: Why screening is not diagnosis.Pediatric investigation · 2026Review
- Personalized Lifespan Approach to Autism Assessment: A Clinical and System Framework for Developmentally Informed Assessment Across the Life-Course.Autism research : official journal of the International Society for Autism Research · 2026Article
- An Analysis of the Psychometric Properties of the Pediatric Inventory for Parents: Short Form Among Caregivers of Children Diagnosed With Autism Spectrum Disorder.Journal of autism and developmental disorders · 2026Article
- Tactile hypo-responsivity in autism: Examining potential for diagnostic relevance.JCPP advances · 2026Article
- Validating the RISE Communication Play Protocol as a Diagnostic Tool for Autism in Early Childhood: A Pilot Study.Journal of autism and developmental disorders · 2026Article
- Barriers and Innovations Towards Accessing an Autism Diagnosis in Rural Northern Ontario: A Qualitative Study.Child: care, health and development · 2026Article
- Confidence of Pediatric Primary Care Clinicians in Autism Screener Score and Their Own Diagnostic Impressions.Behavioral sciences (Basel, Switzerland) · 2026Article
- AI-Enabled Technologies and Biomarker Analysis for the Early Identification of Autism and Related Neurodevelopmental Disorders.Children (Basel, Switzerland) · 2025Review
- Integration of an Artificial Intelligence-Based Autism Diagnostic Device into the ECHO Autism Primary Care Workflow: Prospective Observational Study.JMIR formative research · 2025Observational
- Integration of an Artificial Intelligence-Based Autism Diagnostic Device into the ECHO Autism Primary Care Workflow: Prospective Observational Study.JMIR formative research · 2025Observational
- Comparison of the clinicians' and experts' assessments of rehabilitation service needs for patients in the middle of China.Scientific reports · 2025Article
- Brief Report: Service Referral and Enrollment Following Autism Diagnosis in Primary Care.Research in autism · 2025Article
- Accuracy of the Screening Tool for Autism in Toddlers and Young Children in the primary care setting.Autism : the international journal of research and practice · 2025Article
- Determinants of Pediatricians' Satisfaction With Managing Developmental and Behavioral Disorders in Saudi Arabia.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- Eye-Tracking Biomarkers and Autism Diagnosis in Primary Care.JAMA network open · 2024Article
- Mixed Methods Analysis of Caregiver Satisfaction With the Early Autism Evaluation Hub System.Journal of patient experience · 2024Article
- Understanding how behaviour therapists use autism spectrum disorder diagnostic information for intervention planning.Frontiers in psychiatry · 2023Article
- Hand Leading in Autism: Associations With Neurocognitive Profiles and Adaptive Abilities.Autism & developmental language impairmentsArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo evaluate the diagnostic accuracy of the Early Autism Evaluation (EAE) Hub system, a statewide network that provides specialized training and collaborative support to community primary care providers in the diagnosis of young children at risk for autism spectrum disorder (ASD).
methodsEAE Hub clinicians referred children, aged 14 to 48 months, to this prospective diagnostic study for blinded follow-up expert evaluation including assessment of developmental level, adaptive behavior, and ASD symptom severity. The primary outcome was agreement on categorical ASD diagnosis between EAE Hub clinician (index diagnosis) and ASD expert (reference standard).
resultsAmong 126 children (mean age: 2.6 years; 77% male; 14% Latinx; 66% non-Latinx white), 82% (n = 103) had consistent ASD outcomes between the index and reference evaluation. Sensitivity was 81.5%, specificity was 82.4%, positive predictive value was 92.6%, and negative predictive value was 62.2%. There was no difference in accuracy by EAE Hub clinician or site. Across measures of development, there were significant differences between true positive and false negative (FN) cases (all Ps < .001; Cohen's d = 1.1-1.4), with true positive cases evidencing greater impairment.
conclusionsCommunity-based primary care clinicians who receive specialty training can make accurate ASD diagnoses in most cases. Diagnostic disagreements were predominately FN cases in which EAE Hub clinicians had difficulty differentiating ASD and global developmental delay. FN cases were associated with a differential diagnostic and phenotypic profile. This research has significant implications for the development of future population health solutions that address ASD diagnostic delays.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.