Evidence map›Paper›PMID 37461691›Full record

ArticlebioRxiv : the preprint server for biology2023

Mitonuclear sex determination? Empirical evidence from bivalves.

Chase H Smith, Raquel Mejia-Trujillo, Sophie Breton, Brendan J Pinto, Mark Kirkpatrick, Justin C Havird

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Chase H SmithDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Raquel Mejia-TrujilloDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Sophie BretonDepartment of Biological Sciences, University of Montreal, Montreal, Canada.
Brendan J PintoSchool of Life Sciences, Arizona State University, Tempe, AZ USA.
Mark KirkpatrickDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Justin C HavirdDepartment of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
The University of Texas at Austin · USMilwaukee Public Museum · USUniversité de Montréal · CA

Funding

Causes and Consequences of Mitochondrial MutationsR35GM142836 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI HAVIRD, JUSTIN C · 2021 to 2025
$2.0M
NIGMS NIH HHS R35 GM142836
6 · The paper itself

Abstract

Genetic elements encoded in nuclear DNA determine the sex of an individual in many animals. In bivalves, however, mitochondrial DNA (mtDNA) has been hypothesized to contribute to sex determination in lineages that possess doubly uniparental inheritance (DUI). In these cases, females transmit a female mtDNA (F mtDNA) to all offspring, while male mtDNA (M mtDNA) is transmitted only from fathers to sons. Because M mtDNA is inherited in the same way as Y chromosomes, it has been hypothesized that mtDNA may be responsible for sex determination. However, the role of mitochondrial and nuclear genes in sex determination has yet to be validated in DUI bivalves. In this study, we used DNA, RNA, and mitochondrial short non-coding RNA (sncRNA) sequencing to explore the role of mitochondrial and nuclear elements in the sexual development pathway of the freshwater mussel

Indexed as

doubly uniparental inheritancemitonuclear interactionsmt-sncRNAsSexual developmentUnionida

Identifiers

PMID37461691
PMCPMC10349986
OpenAlexW4383558556

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.