Evidence map›Paper›PMID 37461657›Full record

ArticlebioRxiv : the preprint server for biology2023

Massive contractions of Myotonic Dystrophy Type 2-associated CCTG tetranucleotide repeats occur via double strand break repair with distinct requirements for helicases.

David Papp, Luis A Hernandez, Theresa A Mai, Terrance J Haanen, Meghan A O'Donnell, Ariel T Duran, Sophia M Hernandez, Jenni E Narvanto, Berenice Arguello, Marvin O Onwukwe and 3 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

David PappDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Luis A HernandezDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Theresa A MaiDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Terrance J HaanenDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Meghan A O'DonnellDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Ariel T DuranDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Sophia M HernandezDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Jenni E NarvantoDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Berenice ArguelloDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Marvin O OnwukweDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Kara KolarDepartment of Biology, Tufts University, Medford, MA 02155.
Sergei M MirkinDepartment of Biology, Tufts University, Medford, MA 02155.
Jane C KimDepartment of Biological Sciences, California State University San Marcos, San Marcos, CA 92078.
Tufts University · USCalifornia State University, San Marcos · US

Funding

Training in Education and Critical Research SkillsK12GM074869 · NIGMS · TUFTS UNIVERSITY BOSTON · PI MOORE, CLAIRE L · 2006 to 2017
$8.5M
North San Diego County Bridges to the Future Program at*R25GM066341 · NIGMS · CALIFORNIA STATE UNIVERSITY SAN MARCOS · PI BROWN, TRACEY K, GARCIA, DENISE · 2002 to 2022
$5.0M
California State University San Marcos MARC U*STAR ProgramT34GM008807 · NIGMS · CALIFORNIA STATE UNIVERSITY SAN MARCOS · PI TRUJILLO, KEITH A · 2001 to 2019
$4.8M
Mechanisms of Myotonic Dystrophy Type 2-causing CCTG DNA Repeat InstabilitySC3GM127198 · NIGMS · CALIFORNIA STATE UNIVERSITY SAN MARCOS · PI KIM, JANE C · 2018 to 2021
$420k
NIGMS NIH HHS K12 GM074869NIGMS NIH HHS R25 GM066341NIGMS NIH HHS SC3 GM127198NIGMS NIH HHS T34 GM008807
6 · The paper itself

Abstract

Myotonic Dystrophy Type 2 (DM2) is a genetic disease caused by expanded CCTG DNA repeats in the first intron of

Indexed as

DNA repairDNA repeatshomologous recombinationmicrosatellites

Identifiers

PMID37461657
PMCPMC10350092
OpenAlexW4383531949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.