Evidence map›Paper›PMID 37461632›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Measuring up: A Comparison of Tapestation 4200 and Bioanalyzer 2100 as Measurement Tools for RNA Quality in Postmortem Human Brain Samples.

Jessica E Walker, Javon C Oliver, Analisa M Stewart, Suet Theng Beh, Richard A Arce, Michael J Glass, Daisy E Vargas, Sanaria H Qiji, Anthony J Intorcia, Claryssa I Borja and 10 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Jessica E Walker
Javon C Oliver
Analisa M Stewart
Suet Theng Beh
Richard A Arce
Michael J Glass
Daisy E Vargas
Sanaria H Qiji
Anthony J Intorcia
Claryssa I Borja
Madison P Cline
Spencer J Hemmingsen
Addison N Krupp
Rylee D McHattie
Monica R Mariner
Ileana Lorenzini
Sidra Aslam
Cecilia Tremblay
Thomas G Beach
Geidy E Serrano

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determining RNA integrity is a critical quality assessment tool for gene expression studies where the experiment's success is highly dependent on sample quality. Since its introduction in 1999, the gold standard in the scientific community has been the Agilent 2100 Bioanalyzer's RNA Integrity Number (RIN) which uses a 1-10 value system with 1 being the most degraded to 10 being the most intact. In 2015, Agilent launched the 4200 Tapestation's RIN equivalent and reported a strong correlation of r

Identifiers

PMID37461632
PMCPMC10350153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.