Evidence map›Paper›PMID 37461612›Full record

ArticlebioRxiv : the preprint server for biology2023

TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells.

Thomas G Scott, Kizhakke Mattada Sathyan, Daniel Gioeli, Michael J Guertin

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Thomas G ScottDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, United States of America.
Kizhakke Mattada SathyanCenter for Cell Analysis and Modeling, University of Connecticut, Farmington, Connecticut, United States of America.
Daniel GioeliDepartment of Microbiology, Immunology, and Cancer, University of Virginia, Charlottesville, Virginia, United States of America.
Michael J GuertinCenter for Cell Analysis and Modeling, University of Connecticut, Farmington, Connecticut, United States of America.
University of Connecticut · USUniversity of the Virgin Islands · VIUniversity of Virginia · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007267 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GARCIA-BLANCO, MARIANO A. · 1985 to 2024
$13.4M
TRAINING IN CELL AND MOLECULAR BIOLOGYT32GM008136 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STUKENBERG, P. TODD · 1985 to 2020
$8.5M
Mechanisms of coordinate gene regulation by transcription factorsR35GM128635 · NIGMS · UNIVERSITY OF VIRGINIA · PI Michael Joseph Guertin · 2018 to 2026
$3.4M
NIGMS NIH HHS R35 GM128635NIGMS NIH HHS T32 GM007267NIGMS NIH HHS T32 GM008136
6 · The paper itself

Abstract

Breast cancer is the most frequently diagnosed cancer in women. The most common subtype is luminal breast cancer, which is typically driven by the estrogen receptor

Indexed as

Breast CancerChromatinEstrogen ReceptorTranscriptionTRPS1

Identifiers

PMID37461612
PMCPMC10349936
OpenAlexW4382934497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.