Evidence map›Paper›PMID 37461557›Full record

ArticlebioRxiv : the preprint server for biology2024

A cerebellar population coding model for sensorimotor learning.

Tianhe Wang, Richard B Ivry

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tianhe WangDepartment of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, California.ORCID 0000-0002-0131-850X
Richard B IvryDepartment of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, California.ORCID 0000-0003-4728-5130
University of California, Berkeley · US

Funding

Human Cerebellar Function in Multiple Task DomainsR35NS116883 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI RICHARD IVRY · 2020 to 2026
$5.3M
Specifying the constraints on cerebellar dependent sensorimotor adaptationR01NS105839 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI IVRY, RICHARD · 2018 to 2019
$709k
NINDS NIH HHS R01 NS105839NINDS NIH HHS R35 NS116883
6 · The paper itself

Abstract

The cerebellum is crucial for sensorimotor adaptation, using error information to keep the sensorimotor system well-calibrated. Here we introduce a population-coding model to explain how cerebellar-dependent learning is modulated by contextual variation. The model consists of a two-layer network, designed to capture activity in both the cerebellar cortex and deep cerebellar nuclei. A core feature of the model is that within each layer, the processing units are tuned to both movement direction and the direction of movement error. The model captures a large range of contextual effects including interference from prior learning and the influence of error uncertainty and volatility. While these effects have traditionally been taken to indicate meta learning or context-dependent memory within the adaptation system, our results show that they are emergent properties that arise from the population dynamics within the cerebellum. Our results provide a novel framework to understand how the nervous system responds to variable environments.

Identifiers

PMID37461557
PMCPMC10349940
OpenAlexW4383227438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.