ReviewCureus2023
Primary Cardiac Angiosarcoma: A Review.
Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A synthetic cohort analysis of postoperative management of primary cardiac angiosarcoma and a case report.Frontiers in oncology · 2025Pooled it
- Multimodality treatment and survival in primary cardiac malignancies: evidence from competing-risk and machine learning analyses.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Cytological Diagnosis of Primary Cardiac Angiosarcoma Presenting With Multiple Serous Effusions: A Case Report With Cell Block.Diagnostic cytopathology · 2026Article
- Coexisting benign and malignant tumours: a cardiac angiosarcoma case report.European heart journal. Case reports · 2026Article
- Primary Cardiac Angiosarcoma Leading to Tamponade and Fatal Right Atrial Rupture.JACC. Case reports · 2026Article
- Primary Epithelioid Angiosarcoma of the Right Atrium Presenting With Symptomatic Bradycardia: A Case Report.Cureus · 2026Article
- Primary Pericardial Angiosarcoma Demonstrating Initial Response Followed by Progression on First-Line Chemotherapy: A Case Report.Clinical case reports · 2026Article
- Article
- Long-Term Survival after Repeat Resection and Multimodal Therapy for Primary Cardiac Angiosarcoma: A Case Report.Surgical case reports · 2026Article
- Case Report: Cardiac angiosarcoma with rib pain as the first symptom.Frontiers in oncology · 2026Article
- Dual Left Atrial Masses Causing Inflow Obstruction: A Rare Presentation of Primary Cardiac Intimal Sarcoma.Vascular health and risk management · 2026Article
- The bleeding heart: A case of cardiac angiosarcoma presenting with pulmonary hemorrhage and hemoptysis.Radiology case reports · 2025Article
- Retrospective Study Evaluating Outcomes Following Palliative Radiotherapy With or Without Chemotherapy for Dogs With Presumed Cardiac Hemangiosarcoma.Veterinary and comparative oncology · 2025Article
- Primary cardiac angiosarcoma - a diagnostic roller-coaster till fatality.Journal of cardiovascular and thoracic research · 2025Article
- Cardiac angiosarcoma in acute pericardial tamponade with hemoptysis: A case report.The Journal of international medical research · 2025Article
- Review
- Case report: Diversity of imaging in cardiac angiosarcoma: two cases with disparate enhancement and metabolic manifestations.Frontiers in oncology · 2025Article
- Undifferentiated Pleomorphic Cardiac Sarcoma: A Rare and Often Fatal Diagnosis.JACC. Case reports · 2024Article
- Surgical Resected Cardiac Angiosarcoma in a 75-Year-Old Patient With a Mitral Valve Bioprosthesis.JACC. Case reports · 2024Article
- Complexity in interpreting cardiac valve-associated thrombus from tumors in Li-Fraumeni syndrome.World journal of clinical cases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary cardiac angiosarcoma is a rare and aggressive malignancy originating from the endothelial lining of cardiac blood vessels. This review covers various aspects of the disease, including its pathogenesis, clinical presentation, diagnosis, treatment, and prognosis. The primary characteristic of cardiac angiosarcoma is the rapid growth of abnormal blood vessels that invade the heart muscle, leading to the destruction of healthy tissue. Due to its infiltrative nature and early spread, diagnosing and treating cardiac angiosarcoma present significant challenges. Transesophageal echocardiography (TEE) plays a crucial role in diagnosing cardiac tumors such as angiosarcoma due to its high sensitivity. Additional imaging techniques such as computed tomography (CT) and cardiac magnetic resonance imaging (MRI) help assess tumor anatomy and identify metastases. Histopathological examination and immunohistochemistry are essential for confirming the diagnosis, as they reveal distinct histological features and specific endothelial markers associated with primary cardiac angiosarcoma. Targeted therapies directed at the angiogenic mechanisms and molecular abnormalities hold promise for improving treatment outcomes. Early detection of primary cardiac angiosarcoma remains challenging due to its rarity, and the prognosis is generally poor due to advanced disease at the time of diagnosis. The review emphasizes the importance of a multidisciplinary approach and collaboration among different specialties to optimize the diagnosis, treatment, and follow-up care of patients with primary cardiac angiosarcoma. The ultimate goal is to enhance diagnostic methods and therapeutic approaches by advancing knowledge and promoting further research into this aggressive malignancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.