Evidence map›Paper›PMID 37461345›Full record

ReviewCurrent drug research reviews2024

Unveiling Wide Spectrum Therapeutic Implications and Signaling Mechanisms of Valsartan in Diverse Disorders: A Comprehensive Review.

Kuldeep Kumar, Pooja Rawat, Simrat Kaur, Nirmal Singh, Harlokesh Narayan Yadav, Dhandeep Singh, Amteshwar Singh Jaggi, Dimple Sethi

Abstract readReview
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In one paragraph

Review in Current drug research reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kuldeep KumarDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Pooja RawatDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Simrat KaurDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Nirmal SinghDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Harlokesh Narayan YadavDepartment of Pharmacology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Dhandeep SinghDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Amteshwar Singh JaggiDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Dimple SethiDepartment of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valsartan is an orally active non-peptide angiotensin receptor antagonist, an effective and well-tolerated anti-hypertensive drug. Besides its antihypertensive action, it has clinical implications in many other disorders, like heart failure (HF), arrhythmia, chronic kidney disease (CKD), diabetic complications (DM), atherosclerosis, etc. Besides angiotensin receptor blocking activity, valsartan reduces circulating levels of biochemical markers, such as hs-CRP, which is responsible for its anti-inflammatory and anti-oxidant activity. Moreover, valsartan also acts by inhibiting or inducing various signalling pathways, such as inducing autophagy

Indexed as

Signal TransductionValsartanAnimalsAntihypertensive AgentsHumansAntihypertensive AgentsValsartanAngiotensin-II type-1 receptoratherosclerosischronic kidney diseasediabetes mellitusnon-peptide angiotensin receptor.valsartan

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.