ArticleeLife2023
FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in
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In one paragraph
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 18 citations in OpenAlex.
- Upstream non-AUG initiation and ribosomal -1 frameshifting in ATXN8OS CTA/CTG repeat-associated translation.Nucleic acids research · 2026Article
- RNA G-quadruplexes function as a tunable switch of FUS phase separation.Nucleic acids research · 2026Article
- Visualizing TERRA RNA G-quadruplex Unfolding in FUS Biomolecular Condensates.Journal of molecular biology · 2026Article
- Microprotein Regulates G-quadruplex Driven RNA Aggregation.bioRxiv : the preprint server for biology · 2026Article
- G-Quadruplexes Abet Neuronal Burnout in ALS and FTD.Antioxidants (Basel, Switzerland) · 2025Review
- RNA G-Quadruplexes Function as a Tunable Switch of FUS Phase Separation.bioRxiv : the preprint server for biology · 2025Article
- Visualizing TERRA RNA G-quadruplex unfolding in FUS biomolecular condensates.bioRxiv : the preprint server for biology · 2025Article
- G-quadruplex structural motifs modulate protein-RNA interactions within the transcriptome.Genome biology · 2025Article
- Integrative assessment of RNA sequencing and in silico analysis to pinpoint mRNAs, lncRNAs, and circRNAs interactions with miRNAs underlying arsenic-induced neurotoxicity.BMC genomics · 2025Article
- Canonical translation factors eIF1A and eIF5B modulate the initiation step of repeat-associated non-AUG translation.Nucleic acids research · 2025Article
- Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability.Frontiers in molecular neuroscience · 2025Article
- FUS and METTL3 collaborate to regulate RNA maturation, preventing unfolded protein response and promoting gastric cancer progression.Clinical and experimental medicine · 2024Article
- Decoding Nucleotide Repeat Expansion Diseases: Novel Insights fromInternational journal of molecular sciences · 2024Review
- Cross-Effects in Folding and Phase Transitions of hnRNP A1 and C9Orf72 RNA G4 In Vitro.Molecules (Basel, Switzerland) · 2024Article
- Review
- Vcp overexpression and leucine supplementation extend lifespan and ameliorate neuromuscular junction phenotypes of a SOD1G93A-ALS mouse model.Human molecular genetics · 2024Article
- Protein G-quadruplex interactions and their effects on phase transitions and protein aggregation.Nucleic acids research · 2024Article
- G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes.Nucleic acids research · 2024Article
- Protein G-quadruplex interactions and their effects on phase transitions and protein aggregation.bioRxiv : the preprint server for biology · 2024Article
- dCas13-mediated translational repression for accurate gene silencing in mammalian cells.Nature communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 10 institutions in 2 countries.
Yuzo FujinoDepartment of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.ORCID 0000-0002-1773-8998
Morio UeyamaDepartment of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Taro IshiguroDepartment of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.
Daisaku OzawaDepartment of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Hayato ItoSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.ORCID 0000-0002-1437-5853
Toshihiko SugikiLaboratory of Molecular Biophysics, Institute for Protein Research, Osaka University, Osaka, Japan.ORCID 0000-0003-1716-1241
Asako MurataDepartment of Regulatory Bioorganic Chemistry, The Institute of Scientific and28 Industrial Research, Osaka University, Osaka, Japan.
Akira IshiguroResearch Center for Micro-nano Technology, Hosei University, Tokyo, Japan.
Tania GendronDepartment of Neuroscience, Mayo Clinic, Jacksonville, United States.
Kohji MoriDepartment of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0003-2629-0723
Eiichi TokudaDepartment of Chemistry, Keio University, Kanagawa, Japan.
Tomoya TaminatoDepartment of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Takuya KonnoDepartment of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, Niigata, Japan.
Akihide KoyamaDepartment of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, Niigata, Japan.
Yuya KawabeDepartment of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.ORCID 0000-0002-5438-4797
Toshihide TakeuchiDepartment of Neurotherapeutics, Osaka University Graduate School of Medicine, Suita, Japan.
Yoshiaki FurukawaDepartment of Chemistry, Keio University, Kanagawa, Japan.
Toshimichi FujiwaraLaboratory of Molecular Biophysics, Institute for Protein Research, Osaka University, Osaka, Japan.ORCID 0000-0001-7739-3525
Manabu IkedaDepartment of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.
Toshiki MizunoDepartment of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hideki MochizukiDepartment of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan.
Hidehiro MizusawaDepartment of Neurology and Neurological Science, Tokyo Medical and Dental University, Tokyo, Japan.
Keiji WadaDepartment of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.
Kinya IshikawaDepartment of Neurology and Neurological Science, Tokyo Medical and Dental University, Tokyo, Japan.
Osamu OnoderaDepartment of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, Niigata, Japan.ORCID 0000-0003-3354-5472
Kazuhiko NakataniDepartment of Regulatory Bioorganic Chemistry, The Institute of Scientific and28 Industrial Research, Osaka University, Osaka, Japan.
Leonard PetrucelliDepartment of Neuroscience, Mayo Clinic, Jacksonville, United States.
Hideki TaguchiSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.ORCID 0000-0002-6612-9339
Yoshitaka NagaiDepartment of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.ORCID 0000-0003-1037-3129
The University of Osaka · JPNanotherapeutics (United States) · USNational Center of Neurology and Psychiatry · JPNiigata University · JPTokyo Medical and Dental University · JPKeio University · JPKyoto Prefectural University of Medicine · JPTokyo Institute of Technology · JPWinnMed · USMicron (United States) · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abnormal expansions of GGGGCC repeat sequence in the noncoding region of the
Indexed as
Amyotrophic Lateral SclerosisFrontotemporal DementiaC9orf72 ProteinDrosophilaHumansRNARNA-Binding Protein FUSRNA-Binding ProteinsC9orf72 ProteinC9orf72 protein, humanFUS protein, humanRNARNA-Binding Protein FUSRNA-Binding ProteinsALSC9orf72D. melanogasterFUSneuroscienceRAN translationrepeat expansion diseaseRNA chaperone
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.