Evidence map›Paper›PMID 37461293›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

A novel endoleak classification for intracranial aneurysm flow diversion: A retrospective case series.

Ahmed Kashkoush, Nina Z Moore, Mohamed E El-Abtah, Rebecca Achey, Gabor Toth, Mark Bain

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Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ahmed KashkoushDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Nina Z MooreDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Mohamed E El-AbtahCase Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0000-0001-8451-7012
Rebecca AcheyDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Gabor TothDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Mark BainDepartment of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAlthough flow diversion (FD) is safe and effective in the treatment of intracranial aneurysms, a subset tends to continue filling on serial angiography. Risk factors for failed flow diversion include old age, large aneurysm size, and overstenting an adjacent end-arterial vessel. The hemodynamic modes of persistent aneurysm filling, or 'endoleaks', after FD are poorly understood. This study aims to characterize the various types of endoleaks following aneurysmal FD.MethodsWe performed a retrospective review of a prospectively maintained database of all endovascular procedures performed at a single institution between 2017 and 2021. Patients were included if they demonstrated evidence of unique modes of intracranial aneurysm filling after FD. Data regarding treatment, follow-up angiography, as well as clinical course were collected.ResultsFive patients (mean age 50 years, four females) were included with mean 19-month angiographic follow-up. Five major endoleak types are proposed: Type 1 - due to graft porosity (A - low flow, B - high flow), Type 2 -through an overstented branch vessel, Type 3 - via stent migration no longer covering aneurysmal neck, Type 4 - endoleak due to malapposition of the stent wall, and Type 5 - endoleak via collateralization from adjacent blood vessels. All endoleak types were represented, except for the Type 4 endoleak.ConclusionWe propose an endoleak classification scheme to describe the hemodynamic modes of failure following FD of intracranial aneurysms. Future studies are needed to evaluate the natural history of aneurysmal filling following FD and retreatment success according to endoleak type.

Indexed as

EndoleakEndovascular ProceduresIntracranial AneurysmAdultAgedBlood Vessel ProsthesisCerebral AngiographyFemaleHumansMaleMiddle AgedRetrospective StudiesStentsaneurysmdeviceflow diverter

Identifiers

PMID37461293
PMCPMC12602952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.