Evidence map›Paper›PMID 37461038›Full record

ArticleBMC pediatrics2023

Pediatric ACEs and related life event screener (PEARLS) latent domains and child health in a safety-net primary care practice.

Morgan Ye, Danielle Hessler, Derek Ford, Mindy Benson, Kadiatou Koita, Monica Bucci, Dayna Long, Nadine Burke Harris, Neeta Thakur

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In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Morgan YeSan Francisco Departments of Medicine and Epidemiology and Biostatistics, University of California, 500 Parnassus Avenue, 94143-0841, San Francisco, CA, USA.
Danielle HesslerSan Francisco Department of Family and Community Medicine, University of California, 500 Parnassus Avenue, 94143, San Francisco, CA, USA.
Derek FordCenter for Psychological and Social Health, LLC, 2918 Westover Dr, Danville, VA, 24541, USA.
Mindy BensonSan Francisco Department of Pediatrics, University of California, 5220 Claremont Ave, Oakland, CA, 94609, USA.
Kadiatou KoitaCenter for Youth Wellness, 3450 3rd St, 94124, San Francisco, CA, USA.
Monica BucciCenter for Youth Wellness, 3450 3rd St, 94124, San Francisco, CA, USA.
Dayna LongSan Francisco Department of Pediatrics, University of California, 5220 Claremont Ave, Oakland, CA, 94609, USA.
Nadine Burke HarrisCenter for Youth Wellness, 3450 3rd St, 94124, San Francisco, CA, USA.
Neeta ThakurSan Francisco Departments of Medicine and Epidemiology and Biostatistics, University of California, 500 Parnassus Avenue, 94143-0841, San Francisco, CA, USA. Neeta.Thakur@ucsf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch examining the connections between individual adverse childhood experiences (ACEs) and how groupings of interrelated adversities are linked with subsequent health is scarce, limiting our understanding of risk during a period of rapid expansion of ACE screening in clinical practice. The study objective was to conduct a psychometric analysis to derive latent domains of ACEs and related life events and assess the association between each domain and health outcome.

methodsParticipants (3 months-11 years) were recruited from the University of California San Francisco Benioff's Children Hospital Oakland Primary Care Clinic. Children were screened with the Pediatric ACEs and Related Life Events Screener (PEARLS) (n = 340), which assessed 17 total ACEs and related life events, including forms of abuse, household challenges, and social risks. Domains were constructed using confirmatory factor analysis and associations between the three identified domains and 14 health outcomes were assessed using multivariable linear and logistic regression models.

resultsThree PEARLS domains were identified: Maltreatment (ω = 0.73, ɑ=0.87), Household Challenges (ω = 0.70, ɑ=0.82), and Social Context (ω = 0.55, ɑ=0.70). Measurement invariance was supported across both gender and screening format. All domains were associated with poorer general and behavioral health and stomachaches. Maltreatment and Social Context were additionally associated with eczema while only Social Context was associated with increased odds of reporting headaches and somatic symptoms.

conclusionIn an underserved, urban west-coast pediatric population, the PEARLS found three adversity domains of Maltreatment, Household Challenges, and Social Context that all had an independent statistically significant association with poorer child health. The results provide a timely and more nuanced representation of risk that can inform clinical practice and policy using more targeted resources and interventions.

Indexed as

Adverse Childhood ExperiencesChild HealthLife Change EventsChildChild AbuseChild, PreschoolFactor Analysis, StatisticalFemaleHumansInfantMalePrimary Health CarePsychometricsSafety-net ProvidersSan FranciscoACEsAdverse childhood experiencesChild abuseFactor analysisPEARLS

Identifiers

PMID37461038
PMCPMC10351141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.