Evidence map›Paper›PMID 37460823›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2023

Relationship between the lower limit of systolic blood pressure target and kidney function decline in advanced chronic kidney disease: an instrumental variable analysis from the REACH-J CKD cohort study.

Shimon Kurasawa, Yoshinari Yasuda, Sawako Kato, Shoichi Maruyama, Hirokazu Okada, Naoki Kashihara, Ichiei Narita, Takashi Wada, Kunihiro Yamagata, REACH-J CKD collaborators

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Role of time in target range in blood pressure management for preventing renal decline in type 2 diabetes.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  3. Article
  4. Glomerular pressure and tubular oxygen supply: a critical dual target for renal protection.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  5. Elucidating the complex interplay between chronic kidney disease and hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 20 institutions in 1 country.

Shimon KurasawaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan. kurasawa23@med.nagoya-u.ac.jp.
Yoshinari YasudaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sawako KatoDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shoichi MaruyamaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hirokazu OkadaDepartment of Nephrology, Saitama Medical University, Saitama, Japan.
Naoki KashiharaDepartment of Nephrology and Hypertension, Kawasaki Medical School, Okayama, Japan.
Ichiei NaritaDivision of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan.
Takashi WadaDepartment of Nephrology and Laboratory Medicine, Kanazawa University, Ishikawa, Japan.
Kunihiro YamagataDepartment of Nephrology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
REACH-J CKD collaborators
Nagoya University · JPInoue Hospital · JPKyushu University Hospital · JPNihon University · JPShinmatsudo Central General Hospital · JPUniversity of Tsukuba · JPAsahi General Hospital · JPKawasaki Medical School · JPNagaoka Red Cross Hospital · JPOkayama University Hospital · JPShinonoi General Hospital · JPTokuyama (Japan) · JPUniversity Hospital Kyoto Prefectural University of Medicine · JPUniversity of Miyazaki Hospital · JPHokkaido hospital · JPKanazawa University · JPKobe University Hospital · JPMito Saiseikai General Hospital · JPNagoya Medical Center · JPNagoya University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intensive antihypertensive treatment decreases cardiovascular disease and mortality risks in chronic kidney disease (CKD), whereas extremely low systolic blood pressure (SBP) is associated with worsening kidney function and poor prognosis. Although the SBP variation is particularly large in patients with CKD, the optimal lower limit of SBP target is unclear. In a nationwide, multicenter cohort study of patients with an estimated glomerular filtration rate (eGFR) < 45 mL/min/1.73 m

Indexed as

Cardiovascular DiseasesHypertensionRenal Insufficiency, ChronicAgedBlood PressureCohort StudiesFemaleGlomerular Filtration RateHumansKidneyMaleeGFR slopeinstrumental variablelowest SBPmixed-effects model

Identifiers

PMID37460823
OpenAlexW4384500482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.