ArticleAging clinical and experimental research2023
Intrinsic capacity and 5-year late-life functional ability trajectories of Chinese older population using ICOPE tool: the Rugao Longevity and Ageing Study.
Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Transitions and trajectories in intrinsic capacity states over time: a systematic review.BMC geriatrics · 2025Pooled it
- The assessment and detection rate of intrinsic capacity deficits among older adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Validity of the Derby Scale of Intrinsic Capacity and its association with Pain: a usable measurement of intrinsic capacity based on the English Longitudinal Study of Ageing.European geriatric medicine · 2026Article
- Intrinsic capacity across the adult lifespan in China: baseline analysis from the nationwide longitudinal PENG ZU cohort.GeroScience · 2026Article
- Socioeconomic status and intrinsic capacity trajectories among middle-aged and older adults in China: mediating role of cognitive leisure activities.The journal of nutrition, health & aging · 2026Article
- Article
- Association between intrinsic capacity and sarcopenia in older adults with type 2 diabetes: A cross-sectional study.Aging clinical and experimental research · 2025Article
- Trajectories of intrinsic capacity decline and related factors in old persons: A 15-year community-based cohort study in Beijing.The journal of nutrition, health & aging · 2025Article
- Intrinsic capacity trajectories and cardiovascular disease incidence among Chinese older adults: a population-based prospective cohort study.BMC geriatrics · 2025Article
- The association between sleep duration trajectories and intrinsic capacity in middle-aged and older adults in China: a longitudinal Chinese study assessing healthy aging.Frontiers in medicine · 2025Article
- Multi-trajectories of intrinsic capacity and their effect on higher-level functional capacity, life satisfaction, and self-esteem in community-dwelling older adults: the NILS-LSA.The journal of nutrition, health & aging · 2025Article
- Intrinsic capacity and recent falls in adults 80 years and older living in the community: results from the ilSIRENTE Study.Aging clinical and experimental research · 2024Article
- Aging trajectories and functional capacity: insights from the Otassha study.Aging clinical and experimental research · 2024Article
- Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes.Clinical interventions in aging · 2024Article
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8 authors at 1 institution in 1 country.
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Abstract
BACKGROUND AND
aimsKnowledge of how intrinsic capacity (IC) shape functional ability (FA) trajectories in later life remains unclear. We investigated the changes in IC and their impact on 5-years FA trajectories in the Chinese older population.
methodsA total of 1640 older adults from the Rugao Longitudinal Ageing Study were included and analyzed. FA was assessed by The Lawton Instrumental Activities of Daily Living Scale (IADLs). We used cognition, psychology, locomotion, sensory capacity, and vitality to capture the multiple domains of IC according to the ICOPE method. The IC was derived retrospectively from variables collected before this was described by WHO.
resultsAt baseline, a higher IC was associated with higher IADLs (β = 0.98, 95% CI 0.90, 1.06, P < 0.001). Individuals with declines in IC between wave1 and wave2 experienced a faster decline in IADLs over time (β = - 0.28, 95% CI - 0.40, - 0.16, P < 0.001) after considering covariates. One or more impairment IC scores at baseline strongly predicted death (HR = 1.20, 95% CI 1.11, 1.30, P < 0.001). In addition, according to the IC scores at baseline, we stratify IC in low, middle, and high, compared with those in the high IC score, those in the low were associated with a 2.56-fold (95% CI 1.64, 4.01, P < 0.001) higher risk of mortality, after adjustment for variables.
conclusionChanges in IC shape FA trajectories. IC impairment is associated with an increased risk of death. Assessing intrinsic capacity would facilitate early identification of older adults at high risk of adverse outcomes and prompt targeted interventions.
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