Evidence map›Paper›PMID 37460695›Full record

ArticleNature cell biology2023

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription.

Chuan-Yang Dai, Chai Chee Ng, Grace Ching Ching Hung, Ina Kirmes, Laetitia A Hughes, Yunguang Du, Christopher A Brosnan, Arnaud Ahier, Anne Hahn, Cole M Haynes and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Chuan-Yang DaiClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0001-8768-6196
Chai Chee NgClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Grace Ching Ching HungClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-9732-5535
Ina KirmesClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Laetitia A HughesHarry Perkins Institute of Medical Research, QEII Medical Centre, The University of Western Australia, Nedlands, Western Australia, Australia.
Yunguang DuDepartment of Molecular, Cell and Cancer Biology, UMass Chan Medical School, Worchester, MA, USA.
Christopher A BrosnanClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Arnaud AhierClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Anne HahnClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Cole M HaynesDepartment of Molecular, Cell and Cancer Biology, UMass Chan Medical School, Worchester, MA, USA.ORCID http://orcid.org/0000-0003-2110-5648
Oliver RackhamHarry Perkins Institute of Medical Research, QEII Medical Centre, The University of Western Australia, Nedlands, Western Australia, Australia.
Aleksandra FilipovskaHarry Perkins Institute of Medical Research, QEII Medical Centre, The University of Western Australia, Nedlands, Western Australia, Australia.ORCID http://orcid.org/0000-0002-6998-8403
Steven ZurynClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia. s.zuryn@uq.edu.au.ORCID http://orcid.org/0000-0002-3551-6790
The University of Queensland · AUThe Kids Research Institute Australia · AUUniversity of Massachusetts Chan Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to balance conflicting functional demands is critical for ensuring organismal survival. The transcription and repair of the mitochondrial genome (mtDNA) requires separate enzymatic activities that can sterically compete

Indexed as

Caenorhabditis elegans ProteinsDNA, MitochondrialAnimalsCaenorhabditis elegansCyclic AMP Response Element-Binding ProteinDNA DamageMitochondriaMitochondrial ProteinsCaenorhabditis elegans ProteinsCyclic AMP Response Element-Binding ProteinDNA, MitochondrialMitochondrial Proteins

Identifiers

PMID37460695
OpenAlexW4384561797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.