Evidence map›Paper›PMID 37460466›Full record

ArticleBlood cancer journal2023

Global disparities in patients with multiple myeloma: a rapid evidence assessment.

Maria-Victoria Mateos, Sikander Ailawadhi, Luciano J Costa, Shakira J Grant, Lalit Kumar, Mohamad Mohty, Didem Aydin, Saad Z Usmani

Abstract read
In one paragraph

Article in Blood cancer journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Impact of health insurance coverage on dentition status prior to hematopoietic cell transplant: A 10-year single-institution observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Multiple myeloma.Nature reviews. Disease primers · 2024
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria-Victoria MateosUniversity Hospital of Salamanca/IBSAL, Salamanca, Spain. mvmateos@saludcastillayleon.es.ORCID 0000-0003-2390-1218
Sikander AilawadhiDivision of Hematology/Oncology, Department of Medicine, Mayo Clinic, Jackson, FL, USA.ORCID 0000-0002-8377-8111
Luciano J CostaO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0001-5362-2469
Shakira J GrantDepartment of Medicine, Division of Hematology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-8481-3046
Lalit KumarDepartment of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Mohamad MohtySorbonne University, Department of Hematology, Saint-Antoine Hospital, Paris, France.ORCID 0000-0002-7264-808X
Didem AydinPfizer Pharmaceuticals, Istanbul, Turkey.
Saad Z UsmaniMyeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. usmanis@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Yi Lin · 2015 to 2026
$25.5M
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA186781
6 · The paper itself

Abstract

There are disparities in outcomes for patients with multiple myeloma (MM). We evaluated the influence of sociodemographic factors on global disparities in outcomes for patients with MM. This rapid evidence assessment (PROSPERO, CRD42021248461) followed PRISMA-P guidelines and used the PICOS framework. PubMed and Embase® were searched for articles in English from 2011 to 2021. The title, abstract, and full text of articles were screened according to inclusion/exclusion criteria. The sociodemographic factors assessed were age, sex, race/ethnicity, socioeconomic status, and geographic location. Outcomes were diagnosis, access to treatment, and patient outcomes. Of 84 articles included, 48 were US-based. Worldwide, increasing age and low socioeconomic status were associated with worse patient outcomes. In the US, men typically had worse outcomes than women, although women had poorer access to treatment, as did Black, Asian, and Hispanic patients. No consistent disparities due to sex were seen outside the US, and for most factors and outcomes, no consistent disparities could be identified globally. Too few studies examined disparities in diagnosis to draw firm conclusions. This first systematic analysis of health disparities in patients with MM identified specific populations affected, highlighting a need for additional research focused on assessing patterns, trends, and underlying drivers of disparities in MM.

Indexed as

Health Status DisparitiesMultiple MyelomaAsianBlack or African AmericanEthnicityFemaleHealthcare DisparitiesHispanic or LatinoHumansMaleMeta-Analysis as TopicSex FactorsSystematic Reviews as Topic

Identifiers

PMID37460466
PMCPMC10352266

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.