ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2023
Qualitatively Different Delay-Dependent Working Memory Distortions in People With Schizophrenia and Healthy Control Participants.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The role of attention in perceptual biases in patients with schizophrenia spectrum disorder and healthy controls.European archives of psychiatry and clinical neuroscience · 2026Article
- Convergent multidimensional neural phenotypes in human patients and schizophrenia-relevant mouse models identify reduced recurrent excitation in cortical circuits.medRxiv : the preprint server for health sciences · 2026Article
- Antibody-Mediated Mechanisms in Autoimmune Neurological Disorders.The European journal of neuroscience · 2026Review
- Task-dependent neural dynamics in hippocampal CA1 during auditory and visual perceptual decision-making in rats.Brain structure & function · 2026Article
- Prior Trial Effects on Working Memory in Schizophrenia, Bipolar Disorder, and Healthy Control Individuals.JAMA psychiatry · 2026Article
- Clashing memories in working memory modulate serial dependence.Scientific reports · 2026Article
- Article
- Large-scale mega-analysis indicates that serial dependence deteriorates perceptual decision-making.Nature human behaviour · 2026Article
- Is repulsive serial bias in visual perception driven by adaptation mechanisms?Journal of vision · 2026Article
- Reduced weighting of short-term perceptual priors during auditory perceptual decision-making in psychosis-prone individuals.BMC biology · 2025Article
- Between repulsion and attraction in serial biases: Replication of Chen and Bae (2024).Journal of vision · 2025Article
- Intact Serial Dependence in Schizophrenia: Evidence from an Orientation Adjustment Task.Schizophrenia bulletin · 2025Article
- Serial bias and response time: Prior stimulus not only biases but also modulates the speed of decision for a new stimulus.Journal of vision · 2025Article
- Opposite-Direction Spatial Working Memory Biases in People With Schizophrenia and Healthy Control Participants.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Serial dependence: A matter of memory load.Heliyon · 2024Article
- Continuity fields enhance visual perception through positive serial dependence.Nature reviews. Psychology · 2024Article
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7 authors.
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Abstract
backgroundImpairments in working memory (WM) have been well documented in people with schizophrenia (PSZ). However, these quantitative WM impairments can often be explained by nonspecific factors, such as impaired goal maintenance. Here, we used a spatial orientation delayed response task to explore a qualitative difference in WM dynamics between PSZ and healthy control participants (HCs). More specifically, we took advantage of the discovery that WM representations may drift either toward or away from previous trial targets (serial dependence). We tested the hypothesis that WM representations would drift toward the previous trial target in HCs but away from the previous trial target in PSZ.
methodsWe assessed serial dependence in PSZ (n = 31) and HCs (n = 25) using orientation as the to-be-remembered feature and memory delays lasting from 0 to 8 seconds. Participants were asked to remember the orientation of a teardrop-shaped object and reproduce the orientation after a delay period of varying length.
resultsConsistent with prior studies, we found that current trial memory representations were less precise in PSZ than in HCs. We also found that WM for the current trial orientation drifted toward the previous trial orientation in HCs (representational attraction) but drifted away from the previous trial orientation in PSZ (representational repulsion).
conclusionsThese results demonstrate a qualitative difference in WM dynamics between PSZ and HCs that cannot be easily explained by nuisance factors such as reduced effort. Most computational neuroscience models also fail to explain these results because they maintain information solely by means of sustained neural firing, which does not extend across trials. The results suggest a fundamental difference between PSZ and HCs in longer-term memory mechanisms that persist across trials, such as short-term potentiation and neuronal adaptation.
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