Evidence map›Paper›PMID 37459521›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

An interchangeable prion-like domain is required for Ty1 retrotransposition.

Sean L Beckwith, Emily J Nomberg, Abigail C Newman, Jeannette V Taylor, Ricardo C Guerrero-Ferreira, David J Garfinkel

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Capsid flexibility during Ty1 virus-like particle assembly.bioRxiv : the preprint server for biology · 2025
    Article
  2. GAG Protein ofPlants (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Elimination of virus-like particles reduces protein aggregation and extends replicative lifespan inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. A prion-like domain in Gag capsid protein drives retrotransposon particle assembly and mobility.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sean L BeckwithDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.ORCID 0000-0001-6559-1030
Emily J NombergDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.
Abigail C NewmanDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.
Jeannette V TaylorRobert P. Apkarian Integrated Electron Microscopy Core at Emory University, Atlanta, GA 30322.ORCID 0009-0006-1275-9884
Ricardo C Guerrero-FerreiraRobert P. Apkarian Integrated Electron Microscopy Core at Emory University, Atlanta, GA 30322.ORCID 0000-0002-3664-8277
David J GarfinkelDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.ORCID 0000-0001-6234-2426
University of Georgia · USEmory University · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Effectors of retrotransposon movementR01GM124216 · NIGMS · UNIVERSITY OF GEORGIA · PI GARFINKEL, DAVID J. · 2018 to 2021
$1.9M
FEI Transmission Electron Microscope with Tomography CapabilityS10RR025679 · NCRR · EMORY UNIVERSITY · PI SPEARMAN, PAUL W. · 2009 to 2009
$500k
Retrotransposon virus-like particle assemblyF32GM139247 · NIGMS · UNIVERSITY OF GEORGIA · PI BECKWITH, SEAN · 2020 to 2021
$134k
NCATS NIH HHS UL1 TR000454NCRR NIH HHS S10 RR025679NIGMS NIH HHS F32 GM139247NIGMS NIH HHS R01 GM124216
6 · The paper itself

Abstract

Retrotransposons and retroviruses shape genome evolution and can negatively impact genome function.

Indexed as

RetroelementsSaccharomyces cerevisiaeAnimalsGene Products, gagMammalsMiceRNA, MessengerVirus AssemblyGene Products, gagRetroelementsRNA, Messengerprion-like domainretrotransposonSaccharomyces cerevisiaevirus-like particle

Identifiers

PMID37459521
PMCPMC10372613
OpenAlexW4384498431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.