Evidence map›Paper›PMID 37459465›Full record

ArticleAutophagy2023

Analysis of ATG4C function

Isaac Tamargo-Gómez, Gemma G Martínez-García, María F Suárez, Pablo Mayoral, Gabriel Bretones, Aurora Astudillo, Jesús Prieto-Lloret, Christina Sveen, Antonio Fueyo, Nikolai Engedal and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Autophagy Protease ATG4D Facilitates Proliferation and Malignancy of Osteosarcoma Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Isaac Tamargo-GómezDepartamento de Biología Funcional, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain.ORCID 0000-0002-9907-2543
Gemma G Martínez-GarcíaDepartamento de Biología Funcional, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain.
María F SuárezInstituto de Investigación Sanitaria Del Principado de Asturias (ISPA), Oviedo, Spain.
Pablo MayoralDepartamento de Bioquímica y Biología Molecular, Universidad de Oviedo, Spain.ORCID 0000-0003-3567-3777
Gabriel BretonesInstituto Universitario de Oncología (IUOPA), Oviedo, Spain.ORCID 0000-0002-1521-5544
Aurora AstudilloInstituto Universitario de Oncología (IUOPA), Oviedo, Spain.ORCID 0000-0001-8947-8809
Jesús Prieto-LloretDepartamento de Bioquímica y Biología Molecular y Fisiología, Facultad de Medicina, Universidad de Valladolid. Instituto de Biología y Genética Molecular-CSIC, Valladolid, Spain.ORCID 0000-0002-5281-0211
Christina SveenDepartment of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Montebello, Norway.
Antonio FueyoDepartamento de Biología Funcional, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain.ORCID 0000-0002-7121-9398
Nikolai EngedalDepartment of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Montebello, Norway.ORCID 0000-0003-3718-3464
Carlos López-OtínInstituto Universitario de Oncología (IUOPA), Oviedo, Spain.ORCID 0000-0001-6964-1904
Guillermo MariñoDepartamento de Biología Funcional, Facultad de Medicina, Universidad de Oviedo, Oviedo, Spain.ORCID 0000-0003-1960-1677
Universidad de Oviedo · ESInstituto de Investigación Sanitaria del Principado de Asturias · ESOslo University Hospital · NOUniversidad de Valladolid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abbreviationsATG4 (autophagy related 4 cysteine peptidase); ATG4A (autophagy related 4A cysteine peptidase); ATG4B (autophagy related 4B cysteine peptidase); ATG4C (autophagy related 4C cysteine peptidase); ATG4D (autophagy related 4D cysteine peptidase); Atg8 (autophagy related 8); GABARAP (GABA type A receptor-associated protein); GABARAPL1(GABA type A receptor-associated protein like 1); GABARAPL2 (GABA type A receptor-associated protein like 2); MAP1LC3A/LC3A (microtubule associated protein 1 light chain 3 alpha); MAP1LC3B/LC3B (microtubule associated protein 1 light chain 3 beta); mATG8 (mammalian Atg8); PE (phosphatidylethanolamine); PS (phosphatydylserine); SQSTM1/p62 (sequestosome 1).

Indexed as

AutophagyAutophagy-Related ProteinsAnimalsCysteineCysteine Endopeptidasesgamma-Aminobutyric AcidMammalsMiceMicrotubule-Associated ProteinsAtg4C protein, mouseAutophagy-Related ProteinsCysteineCysteine Endopeptidasesgamma-Aminobutyric AcidMicrotubule-Associated ProteinsAnimal modelsautophagyfibrosarcomaGABARAPLC3lymphocyte

Identifiers

PMID37459465
PMCPMC10549197
OpenAlexW4384498469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.