Evidence map›Paper›PMID 37459310›Full record

Trial reportPloS one2023

Gamified assessment of cognitive performance during moderate hypoxia.

Jason M Keeler, Erica Tourula, M Jo Hite, Jennifer B Listman, David J Heeger, Nicholas L Port, Zachary J Schlader

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jason M KeelerDepartment of Kinesiology, H.H. Morris Human Performance Laboratories, School of Public Health, Indiana University, Bloomington, Indiana, United States of America.ORCID 0000-0002-6788-2306
Erica TourulaDepartment of Kinesiology, H.H. Morris Human Performance Laboratories, School of Public Health, Indiana University, Bloomington, Indiana, United States of America.
M Jo HiteDepartment of Kinesiology, H.H. Morris Human Performance Laboratories, School of Public Health, Indiana University, Bloomington, Indiana, United States of America.
Jennifer B ListmanStatespace Labs, Inc. New York, New York, United States of America.
David J HeegerStatespace Labs, Inc. New York, New York, United States of America.
Nicholas L PortSchool of Optometry, Indiana University, Bloomington, Indiana, United States of America.
Zachary J SchladerDepartment of Kinesiology, H.H. Morris Human Performance Laboratories, School of Public Health, Indiana University, Bloomington, Indiana, United States of America.
Indiana University Bloomington · USMedpace (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is a need for rapid and objective assessment tools to identify people at risk of impaired cognitive function during hypoxia. PURPOSE: To test the hypotheses that performance on gamified cognitive tests examining the cognitive domains of executive function (Gridshot), working memory (Capacity) and spatial tracking (Multitracker) will be reduced during normobaric exposure to moderate normobaric hypoxia.

methodsFollowing three consecutive days of practice, twenty-one healthy adults (27 ± 5 y, 9 females) completed five 1-min rounds of the tablet-based games Gridshot, Capacity, and Multitracker (Statespace Labs, Inc.) at Baseline and 60 and 90 min after exposure to 14.0 ± 0.2% (hypoxia) and 20.6 ± 0.3% (normoxia) oxygen. Both conditions were completed on the same day and were administered in a single-blind, block randomized manner. Arterial oxyhemoglobin saturation was estimated via forehead pulse oximetry (SpO2). Data were analyzed using ANCOVA with a covariate of Baseline.

resultsCompared to normoxia (98 ± 1%), SpO2 was lower (p < 0.001) at 60 (91 ± 3%) and 90 (91 ± 2%) min of hypoxia. No condition x time interaction effects were identified for any gamified cognitive tests (p ≥ 0.32). A main effect of condition was identified for Capacity (p = 0.05) and Multitracker (p = 0.04), but not Gridshot (p = 0.33). Post hoc analyses of the composite scores for both Capacity (p = 0.11) and Multitracker (p = 0.73) demonstrated no difference between conditions.

conclusionPerformance on gamified cognitive tests was not consistently affected by acute normobaric moderate hypoxic exposure.

Indexed as

HypoxiaOxygenAdultCognitionFemaleHumansOximetrySingle-Blind MethodOxygen

Identifiers

PMID37459310
PMCPMC10351691
OpenAlexW4384521655

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.