Evidence map›Paper›PMID 37459254›Full record

ArticleBrain and behavior2023

Structural brain morphology in young adult women who have been choked/strangled during sex: A whole-brain surface morphometry study.

Jiancheng Hou, Megan E Huibregtse, Isabella L Alexander, Lillian M Klemsz, Tsung-Chieh Fu, Molly Rosenberg, James Dennis Fortenberry, Debby Herbenick, Keisuke Kawata

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06602362 (Uncovering the Acute Neurobiological Significance of Emerging Sexual Behaviors), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06602362 nacompletednot on this mapstarted 2024, after this paper: background citation

Uncovering the Acute Neurobiological Significance of Emerging Sexual Behaviors

TypeinterventionalSponsorIndiana UniversityRan2024 to 2025Enrolled31ConditionsSexual Behavior, Hypoxia, BrainArmsPartnered sex involving choking, Partnered sex not involving choking
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jiancheng HouResearch Center for Cross-Straits Cultural Development, Fujian Normal University, Fuzhou, China.
Megan E HuibregtseDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.
Isabella L AlexanderDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.
Lillian M KlemszDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.
Tsung-Chieh FuDepartment of Applied Health Science, Indiana University School of Public Health, Indiana University, Bloomington, Indiana, USA.
Molly RosenbergDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Indiana University, Bloomington, Indiana, USA.
James Dennis FortenberryDepartment of Pediatrics, Indiana University School of Medicine, Indiana University, Indianapolis, Indiana, USA.
Debby HerbenickDepartment of Applied Health Science, Indiana University School of Public Health, Indiana University, Bloomington, Indiana, USA.
Keisuke KawataDepartment of Kinesiology, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.ORCID 0000-0003-4135-9311
Indiana University Bloomington · USIndiana University Health · USEmory University · USFujian Normal University · CNIndiana University School of Medicine

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Subconcussive neurodegenerative progression in adolescent athletesR01NS113950 · NINDS · TRUSTEES OF INDIANA UNIVERSITY · PI KAWATA, KEISUKE · 2021 to 2025
$2.8M
Neuroimaging and blood biomarkers for subconcussive neural stress on ADHDR21NS116548 · NINDS · TRUSTEES OF INDIANA UNIVERSITY · PI KAWATA, KEISUKE, NEWMAN, SHARLENE D · 2020 to 2020
$436k
Sex differences in traumatic brain injury: Neural circuit mediators of overlapping stress and physical effectsF32MH134528 · NIMH · EMORY UNIVERSITY · PI HUIBREGTSE, MEGAN E · 2023 to 2024
$158k
NCATS NIH HHS UL1 TR002529NIMH NIH HHS F32 MH134528NINDS NIH HHS R01 NS113950NINDS NIH HHS R21 NS116548
6 · The paper itself

Abstract

introductionBeing choked/strangled during partnered sex is an emerging sexual behavior, particularly prevalent among young adult women. Using a multiparameter morphometric imaging approach, we aimed to characterize neuroanatomical differences between young adult women (18-30 years old) who were exposed to frequent sexual choking and their choking naïve controls.

methodsThis cross-sectional study consisted of two groups (choking [≥4 times in the past 30 days] vs. choking-naïve group). Participants who reported being choked four or more times during sex in the past 30 days were enrolled in the choking group, whereas those without were assigned to the choking naïve group. High-resolution anatomical magnetic resonance imaging (MRI) data were analyzed using both volumetric features (cortical thickness) and geometric features (fractal dimensionality, gyrification, sulcal depth).

resultsForty-one participants (choking n = 20; choking-naïve n = 21) contributed to the final analysis. The choking group showed significantly increased cortical thickness across multiple regions (e.g., fusiform, lateral occipital, lingual gyri) compared to the choking-naïve group. Widespread reductions of the gyrification were observed in the choking group as opposed to the choking-naïve group. However, there was no group difference in sulcal depth. The fractal dimensionality showed bi-directional results, where the choking group exhibited increased dimensionality in areas including the postcentral gyrus, insula, and fusiform, whereas decreased dimensionality was observed in the bilateral superior frontal gyrus and pericalcarine cortex.

conclusionThese data in cortical morphology suggest that sexual choking events may be associated with neuroanatomical alteration. A longitudinal study with multimodal assessment is needed to better understand the temporal ordering of sexual choking and neurological outcomes.

Indexed as

Airway ObstructionCerebral CortexAdolescentAdultCross-Sectional StudiesFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingSexual BehaviorYoung Adultcortical thicknessnon-fatal strangulationsexual asphyxiationsexual chokingsurface morphometry

Identifiers

PMID37459254
PMCPMC10454256
OpenAlexW4384522117

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.