Evidence map›Paper›PMID 37458576›Full record

ArticleeLife2023

Medullary tachykinin precursor 1 neurons promote rhythmic breathing.

Jean-Philippe Rousseau, Andreea Furdui, Carolina da Silveira Scarpellini, Richard L Horner, Gaspard Montandon

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jean-Philippe RousseauKeenan Research Centre for Biomedical Sciences. St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.
Andreea FurduiKeenan Research Centre for Biomedical Sciences. St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.
Carolina da Silveira ScarpelliniKeenan Research Centre for Biomedical Sciences. St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.ORCID 0000-0001-5576-3468
Richard L HornerDepartment of Physiology, Faculty of Medicine, University of Toronto, Toronto, Canada.
Gaspard MontandonKeenan Research Centre for Biomedical Sciences. St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.ORCID 0000-0003-3587-4472
St Michael’s Hospital · IEUniversity of Toronto · CA

Funding

CIHR
6 · The paper itself

Abstract

Rhythmic breathing is generated by neural circuits located in the brainstem. At its core is the preBötzinger Complex (preBötC), a region of the medulla, necessary for the generation of rhythmic breathing in mammals. The preBötC is comprised of various neuronal populations expressing neurokinin-1 receptors, the cognate G-protein-coupled receptor of the neuropeptide substance P (encoded by the tachykinin precursor 1 or

Indexed as

Receptors, Neurokinin-1Substance PAnimalsMammalsMedulla OblongataMiceNeuronsProtein PrecursorsRespirationRespiratory CenterTachykininsprotachykininProtein PrecursorsReceptors, Neurokinin-1Substance PTachykininsbrainstembreathingmotor behaviorsmouseneuroscienceopioidTac1

Identifiers

PMID37458576
PMCPMC10400077
OpenAlexW4384560560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.