Evidence map›Paper›PMID 37458497›Full record

ArticleAnimals : an open access journal from MDPI2023

Novel Mutation in the Feline

Tofazzal Md Rakib, Md Shafiqul Islam, Mohammad Mejbah Uddin, Mohammad Mahbubur Rahman, Akira Yabuki, Tetsushi Yamagami, Motoji Morozumi, Kazuyuki Uchida, Shinichiro Maki, Abdullah Al Faruq and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Tofazzal Md RakibLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0003-2642-9908
Md Shafiqul IslamLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0003-2248-917X
Mohammad Mejbah UddinLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.
Mohammad Mahbubur RahmanLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.
Akira YabukiLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-6418-5169
Tetsushi YamagamiJapan Small Animal Medical Center, Saitama, Tokorozawa 359-0023, Japan.
Motoji MorozumiTogasaki Animal Hospital, Saitama, Misato 341-0044, Japan.
Kazuyuki UchidaLaboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyō, Tokyo 113-8657, Japan.
Shinichiro MakiLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-1691-1672
Abdullah Al FaruqLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.
Osamu YamatoLaboratory of Clinical Pathology, Joint Faculty of Veterinary Medicine, Kagoshima University, Korimoto, Kagoshima 890-0065, Japan.ORCID 0000-0002-4430-5645
Kagoshima University · JPFujita Animal Hospital · JPJapan Small Animal Medical Center · JPThe University of Tokyo · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology 17H03927
6 · The paper itself

Abstract

Niemann-Pick disease (NP) type C is an autosomal, recessive, and inherited neurovisceral genetic disorder characterized by the accumulation of unesterified cholesterol and glycolipids in cellular lysosomes and late endosomes, with a wide spectrum of clinical phenotypes. This study aimed to determine the molecular genetic alterations in two cases of felines with NP in Japan, a Siamese cat in 1989 and a Japanese domestic (JD) cat in 1998. Sanger sequencing was performed on 25 exons of the feline

Indexed as

feline NPC2 geneJapanese domestic catlysosomal storage diseaseNiemann–Pick disease type CSiamese cat

Identifiers

PMID37458497
PMCPMC10252137
OpenAlexW4378228412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.