ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2023
Changes in sex hormones and their interactions are related to pain perception between different menstrual subphases.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Changes in hormones and experimental pain sensitivity in healthy girls: an exploratory longitudinal pilot study.Pain reports · 2026Article
- Sex differences in pain in 2 large and diverse US databases.Pain reports · 2026Article
- Menstrual cycle hormonal fluctuations and their associations with athletic performance and injury susceptibility in female athletes.Frontiers in sports and active living · 2026Review
- Article
- The Influence of the Menstrual Cycle on Electrical Thresholds for Sensory and Pain Perception: Implications for Exercise and Rehabilitation in Women With and Without Primary Dysmenorrhea-A Pilot Study.Healthcare (Basel, Switzerland) · 2025Article
- The role of androgens on experimental pain sensitivity: a systemic review and meta-analysis.Pain reports · 2025Review
- Adenomyosis in patients with rheumatic diseases: a cross-disciplinary clinical observation.Frontiers in reproductive health · 2025Article
- Sex Hormone Levels and Pain Thresholds in the Luteal Phase of Healthy Women.International journal of women's health · 2025Article
- Sex differences in nerve injury-induced neuropathic pain via REST in primary sensory neurons.Neurobiology of pain (Cambridge, Mass.)Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whether sex hormones are related to pain perception across the menstrual cycle is unclear. We examined changes in experimental pain perception in healthy young females between the early to midfollicular subphase (emF) and the midluteal subphase (mL) and explored the role of sex hormones. Sixty-six participants were involved in the study. We tested pressure pain, cold pain, ischemic pain, and needle pain, while at the same time we measured sex hormones levels in two menstrual subphases. Only the right ulna pressure test showed a significant reduction in pain threshold (PPTh3) during the mL. The absolute change of PPTh3 (PPTh3
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