Evidence map›Paper›PMID 37457942›Full record

ArticleInternational journal of bioprinting2023

Tissue-engineered edible bird's nests (TeeBN).

Yu Liu, Yangyang Liu, Jiayue Liu, Yuwei Li, Jian-Bo Wan, Yiming Niu, Lei Dong, Li Du, Chunming Wang

Open access · diamondAbstract read
In one paragraph

Article in International journal of bioprinting, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yu LiuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
Yangyang LiuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
Jiayue LiuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
Yuwei LiState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
Jian-Bo WanState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
Yiming NiuState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
Lei DongState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, 210093, China.
Li DuFaculty of Law, University of Macau, Taipa, Macau SAR.
Chunming WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medicine & Department of Pharmaceutical Sciences, Faculty of Health Science, University of Macau, Taipa, Macau SAR.
University of Macau · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edible bird's nests (EBN)-the nests of swiftlet birds harvested from the wild- are high-end healthcare food in East Asia, while their excessive harvesting poses increasing ecological, environmental, and food safety concerns. Here, we report for the first time a tissue-engineering (TE) approach for fabricating EBNs substitutes by integrating the technologies of three-dimensional (3D) printing and live cell culture. The engineered products, tissue-engineered edible bird's nests (TeeBN), comprise two layers. The first is a feeding layer that encapsulates epithelial cells in 3D-printed biocompatible gelation scaffolds. These cells secrete bioactive ingredients, e.g., sialic acid and epidermal growth factors (EGF), recapitulating the natural production of these substances by birds. The second is a receiving layer, consisting of foodgrade natural polymers, e.g., polysaccharides, which mimics the building blocks of natural EBNs while biologically stabilizing the factors released from the feeding layer.

Indexed as

3D printingCellular agricultureEdible bird’s nestsFood technologyTissue engineering

Identifiers

PMID37457942
PMCPMC10339468
OpenAlexW4323045646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.