ReviewInternational journal of bioprinting2023
Smart implants: 4D-printed shape-morphing scaffolds for medical implantation.
Review in International journal of bioprinting, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Here today, gone tomorrow: the transformative role of biodegradable materials in modern trauma care.EFORT open reviews · 2026Pooled it
- Integrated fabrication of a shape-adaptable, antioxidative composite stent for effective closure and biological repair of enteroatmospheric fistula.Bioactive materials · 2026Article
- Bioinspired Polymeric Scaffolds for Improvement of Angiogenesis and Tissue Engineering: A Review.Polymers · 2026Review
- From Smart Hydrogel Design to 4D-Printed Scaffolds: Emerging Paradigms in Precision Drug Delivery and Regenerative Wound Therapy.Gels (Basel, Switzerland) · 2026Review
- Toward 4D printed functional soft tissues.Acta biomaterialia · 2026Review
- Acoustic shape-morphing micromachines.Nature communications · 2026Article
- Exercise-Based Mechanotherapy: From Biomechanical Principles and Mechanotransduction to Precision Regenerative Rehabilitation.International journal of molecular sciences · 2026Review
- Recent Advances in Mechanobiology-Mediated In Situ Tissue Engineering.International journal of biomaterials · 2026Review
- 4D-Morphing biopolymers in reconstructive plastic surgery: implications, challenges and a call for clinical-translation.Annals of medicine and surgery (2012) · 2026Article
- Four-Dimensional Printing of Shape Memory Polymers for Biomedical Applications: Advances in DLP and SLA Manufacturing.Polymers · 2025Review
- Transformative bioprinting: 4D printing and its role in the evolution of engineering and personalized medicine.Discover nano · 2025Review
- Biomimetic Additive Manufacturing: Engineering Complexity Inspired by Nature's Simplicity.Biomimetics (Basel, Switzerland) · 2025Article
- Recent advances in 3D printing applications for CNS tumours.European journal of medical research · 2025Review
- From Stents to Smart Implants Employing Biomimetic Materials: The Impact of 4D Printing on Modern Healthcare.Biomimetics (Basel, Switzerland) · 2025Review
- 3D and 4D assembly of functional structures using shape-morphing materials for biological applications.Frontiers in bioengineering and biotechnology · 2024Review
- A Review of Abdominal Meshes for Hernia Repair-Current Status and Emerging Solutions.Materials (Basel, Switzerland) · 2023Review
- From Static to Dynamic: Smart Materials Pioneering Additive Manufacturing in Regenerative Medicine.International journal of molecular sciences · 2023Review
- Promising New Horizons in Medicine: Medical Advancements with Nanocomposite Manufacturing via 3D Printing.Polymers · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomedical implants have recently shown excellent application potential in tissue repair and replacement. Applying three-dimensional (3D) printing to implant scaffold fabrication can help to address individual needs more precisely. Fourdimensional (4D) printing emerges rapidly based on the development of shape-responsive materials and design methods, which makes the production of dynamic functional implants possible. Smart implants can be pre-designed to respond to endogenous or exogenous stimuli and perform seamless integration with regular/ irregular tissue defects, defect-luminal organs, or curved structures via programmed shape morphing. At the same time, they offer great advantages in minimally invasive surgery due to the small-to-large volume transition. In addition, 4D-printed cellular scaffolds can generate extracellular matrix (ECM)-mimetic structures that interact with the contacting cells, expanding the possible sources of tissue/organ grafts and substitutes. This review summarizes the typical technologies and materials of 4D-printed scaffolds, and the programming designs and applications of these scaffolds are further highlighted. Finally, we propose the prospects and outlook of 4D-printed shape-morphing implants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.