Evidence map›Paper›PMID 37457576›Full record

ArticleFrontiers in medicine2023

sTREM-1 and TNF-α levels are associated with the clinical outcome of leprosy patients.

Márcio Bezerra-Santos, Lays G Santos Bomfim, Camilla N Oliveira Santos, Maria Wiliane N Cunha, Eduardo J Rocha de Moraes, Rodrigo A Cazzaniga, Martha D L Tenório, Jonnia M Sherlock Araujo, Lucas Menezes-Silva, Lucas Sousa Magalhães and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Márcio Bezerra-SantosCentro de Ciências Médicas e Enfermagem, Universidade Federal de Alagoas, Maceió, Brazil.
Lays G Santos BomfimLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Camilla N Oliveira SantosLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Maria Wiliane N CunhaLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Eduardo J Rocha de MoraesLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Rodrigo A CazzanigaLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Martha D L TenórioPrograma de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil.
Jonnia M Sherlock AraujoPrograma de Pós-Graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, Brazil.
Lucas Menezes-SilvaLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Lucas Sousa MagalhãesLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Aline S BarretoLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Steven G ReedHost Directed Therapeutics (HDT) Bio Corp, Seattle, WA, United States.
Malcolm S DuthieHost Directed Therapeutics (HDT) Bio Corp, Seattle, WA, United States.
Michael W LipscombDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, United States.
Roque Pacheco de AlmeidaLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Tatiana Rodrigues de MouraLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Amélia Ribeiro de JesusLaboratório de Imunologia e Biologia Molecular, Universidade Federal de Sergipe, Aracaju, Brazil.
Universidade Federal de Sergipe · BRUniversidade Federal de Alagoas · BRUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy reaction (LR) and physical disability (PD) are the most significant clinical complications of leprosy. Herein, we assessed the circulating serum-sTREM-1 and TNF-α levels and their genetic polymorphisms in leprosy. Serum-sTREM-1 and TNF-α levels were measured in leprosy patients (LP) before treatment (

Indexed as

immune markersinflammatory cytokineleprosyleprosy complicationssoluble TREM-1

Identifiers

PMID37457576
PMCPMC10339318
OpenAlexW4382722647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.