Evidence map›Paper›PMID 37457538›Full record

ArticleIndian journal of sexually transmitted diseases and AIDS

Study of serum level of kisspeptin and interferon-beta in genital wart patients.

Heba Allah Saad Eldeen Bazid, Alaa H Marae, Nermin Tayel, Shereen G Zaid, Mohammed I Mostafa, Eman Masoud Abd El Gayed

Open access · hybridAbstract read
In one paragraph

Article in Indian journal of sexually transmitted diseases and AIDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Heba Allah Saad Eldeen BazidDepartment of Dermatology and Andrology, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Alaa H MaraeDepartment of Dermatology and Andrology, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Nermin TayelDepartment of Molecular Diagnostics and Therapeutics, Genetic Engineering and Biotechnology Research Institute, Sadat City, Egypt.
Shereen G ZaidDepartment of Dermatology and Andrology, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Mohammed I MostafaDepartment of Clinical Pathology, Medical Research Division, National Research Centre, Cairo, Egypt.
Eman Masoud Abd El GayedDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Menoufia University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Researchers are interested in genital wart (GW) studies due to their increased incidence. In a single experimental research, virally infected mouse models showed elevated kisspeptin levels and low interferon levels. Objective: The objective of the study was to evaluate the serum levels of kisspeptin and interferon (INF)-beta in GW patients. Patients and Methods: Forty patients with GWs and forty healthy participants of comparable age and sex as a control group were included in this case-control study. Serum levels of kisspeptin and IFN-beta were measured using ELISA during the period from December 2021 to April 2022. Results: Kisspeptin was significantly higher among cases than controls, whereas IFN-beta level was lower among cases than controls ( Conclusion: The reported increased kisspeptin level which was associated with decreased interferon-beta level in patients with GWs might indicate a new insight into viral infection pathogenesis. Further research including all steps in kisspeptin/G protein-coupled receptor 54 pathway is required. Targeted therapy for this pathway may be of value for those patients.

Indexed as

Genital wartsinterferon-betakisspeptin

Identifiers

PMID37457538
PMCPMC10343131
OpenAlexW4379400453

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.