Evidence map›Paper›PMID 37457506›Full record

ReviewTherapeutics and clinical risk management2023

Status and Future Directions of Therapeutics and Prognosis of Cardiac Amyloidosis.

Wenbing Zhang, Jian Ding, Wenhai Wang, Duo Wang, Yinping Pan, Dexin Xu

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutics and clinical risk management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wenbing ZhangDepartment of Cardiology, Jilin Province FAW General Hospital, Changchun, 130000, People's Republic of China.
Jian DingDepartment of Electrodiagnosis, Jilin Province FAW General Hospital, Changchun, 130000, People's Republic of China.
Wenhai WangDepartment of Cardiology, Jilin Province FAW General Hospital, Changchun, 130000, People's Republic of China.
Duo WangDepartment of Geriatrics, Jilin Province FAW General Hospital, Changchun, 130000, People's Republic of China.
Yinping PanDepartment of Pediatrics, Jilin Province FAW General Hospital, Changchun, 130000, People's Republic of China.
Dexin XuDepartment of Orthopedics, Jilin Province FAW General Hospital, Changchun, 130000, People's Republic of China.
People 's Hospital of Jilin Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulation of aberrant proteins in the heart causes cardiac amyloidosis, an uncommon and complicated illness. It can be classified into two main types: light chain (AL) and transthyretin (ATTR). The diagnosis of cardiac amyloidosis is challenging due to its non-specific clinical presentation and lack of definitive diagnostic tests. Diagnostic accuracy has increased with the advent of modern imaging methods, including cardiac magnetic resonance imaging (MRI) and positron emission tomography (PET) scans. Depending on the severity of cardiac amyloidosis, a number of treatments may be attempted and specified according to the subtype of amyloidosis and the presence of complications. However, there are still significant challenges in treating this condition due to its complexity and lack of effective treatments. The prognosis for patients with cardiac amyloidosis is poor. Despite recent advances in diagnosis and treatment, there is still a need for more effective treatments to improve outcomes for patients with this condition. Therefore, we aim to review the current and future therapeutics reported in the literature and among ongoing clinical trials recruiting patients with CA.

Indexed as

AL CAATTR CAcardiac amyloidosischemotherapyimmunomodulatory agentslight-chain amyloidosismanagementstem cell transplantationtransthyretin amyloidosistreatment

Identifiers

PMID37457506
PMCPMC10348342
OpenAlexW4383818805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.