Evidence map›Paper›PMID 37457497›Full record

ArticleJournal of healthcare engineering2023

Expression and Clinical Significance of Ki67 and SOX2 in Colorectal Cancer.

Bo Hu, Xinfu Song, Weiji Ding, Hailong Wang, Huali Cai, Zhengjie Huang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bo HuDepartment of Gastrointestinal Surgery, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361000, China.
Xinfu SongDepartment of Gastrointestinal Surgery, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361000, China.
Weiji DingDepartment of Gastrointestinal Surgery, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361000, China.
Hailong WangDepartment of Gastrointestinal Surgery, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361000, China.
Huali CaiDepartment of Gastrointestinal Surgery, Xiamen Humanity Hospital Fujian Medical University, Xiamen 361000, China.
Zhengjie HuangThe Third Clinical Medical College, Fujian Medical University, Fuzhou 350122, China.ORCID 0000-0002-1992-5834
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the paper is to explore the expression levels and clinical significance of Ki67 and sex-determining region Y-box 2 (SOX2) in colorectal cancer. From January 2013 to December 2016, 176 patients with colorectal cancer who were pathologically diagnosed after surgery in the Department of General Surgery in Xiamen Chinese Medical Hospital are included in this study. The pathological parameters, including gender, age, pathological stage, depth of tumor invasion, lymph node metastasis, and distant metastasis, are recorded. Immunohistochemistry is used to detect the correlation between Ki67 and Sox2 protein expression and clinicopathological parameters in colorectal cancer. Immunohistochemistry shows that in each stage of colorectal cancer, the positive rate of SOX2 is higher than that of Ki67, and the sensitivity of SOX2 is relatively high. Moreover, the levels of Ki67 and SOX2 in the cancerous tissues are not related to gender, age, lymph node metastasis and distant metastasis (

Indexed as

Biomarkers, TumorColorectal NeoplasmsClinical RelevanceHumansKi-67 AntigenLymphatic MetastasisSOXB1 Transcription FactorsBiomarkers, TumorKi-67 AntigenSOX2 protein, humanSOXB1 Transcription Factors

Identifiers

PMID37457497
PMCPMC10348847
OpenAlexW4383532011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.