Evidence map›Paper›PMID 37457479›Full record

ArticleACS omega2023

Biocompatible Alginate Film Crosslinked with Ca

Alba Cano-Vicent, Alberto Tuñón-Molina, Hamid Bakshi, Roser Sabater I Serra, Iman M Alfagih, Murtaza M Tambuwala, Ángel Serrano-Aroca

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Automated active learning to optimize hydrogel drug release profiles.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alba Cano-VicentBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, Valencia 46001, Spain.ORCID https://orcid.org/0000-0001-7662-7748
Alberto Tuñón-MolinaBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, Valencia 46001, Spain.ORCID https://orcid.org/0000-0003-3819-7390
Hamid BakshiHormel Institute, University of Minnesota, Austin, Minnesota 55912, United States.
Roser Sabater I SerraCentre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, València 46022, Spain.ORCID https://orcid.org/0000-0002-5550-7066
Iman M AlfagihDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 4545, Saudi Arabia.
Murtaza M TambuwalaLincoln Medical School, University of Lincoln, Brayford Pool Campus, Lincoln LN6 7TS, U.K.ORCID https://orcid.org/0000-0001-8499-9891
Ángel Serrano-ArocaBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, Valencia 46001, Spain.ORCID https://orcid.org/0000-0002-9953-3848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alginate is a highly promising biopolymer due to its non-toxic and biodegradable properties. Alginate hydrogels are often fabricated by cross-linking sodium alginate with calcium cations and can be engineered with highly desirable enhanced physical and biological properties for biomedical applications. This study reports on the anticancer, antiviral, antibacterial, in vitro, and in vivo toxicity, water absorption, and compound release properties of an alginate hydrogel crosslinked with calcium and different amounts of zinc cations. The results showed that the calcium alginate hydrogel film crosslinked with the highest amount of zinc showed similar water sorption properties to those of calcium alginate and released a suitable amount of zinc to provide anticancer activity against melanoma and colon cancer cells and has antibacterial properties against methicillin-resistant

Identifiers

PMID37457479
PMCPMC10339430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.