Evidence map›Paper›PMID 37457430›Full record

ReviewFrontiers in reproductive health2023

Testicular pathological alterations associated with SARS-CoV-2 infection.

Judy Ly, Rafael K Campos, E Eldridge Hager-Soto, Vidyleison N Camargos, Shannan L Rossi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in reproductive health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Judy LyDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Rafael K CamposDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
E Eldridge Hager-SotoDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Vidyleison N CamargosDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
Shannan L RossiDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, United States.
The University of Texas Medical Branch at Galveston · US

Funding

Medicinal Chemistry Optimization of Anti-Alphaviral Leads and Elucidation of Target and Off Target EngagementU19AI142762 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI GOLDEN, JENNIFER E. · 2019 to 2023
$22.0M
NIAID NIH HHS U19 AI142762
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the etiologic agent of the coronavirus disease 2019 (COVID-19), which caused one of the pandemics with the highest mortalities with millions of deaths and hundreds of millions of cases to date. Due to its potential for airborne transmission, many studies have focused on SARS-CoV-2 primarily as a respiratory disease. However, the spread of SARS-CoV-2 to non-respiratory organs has been experimentally demonstrated and clinically observed. During autopsy studies, histopathological lesions, and disruption of the blood-testes barrier (BTB) have been observed in the male reproductive tract. Here, we review findings from both autopsy cases and animal models that demonstrate testicular disease due to COVID-19 and present an overview of the pathological alterations that occur in the testes resulting from SARS-CoV-2 infection and explore its potential mechanisms.

Indexed as

COVID-19male reproductive tractSARS-CoV-2testestesticular disease

Identifiers

PMID37457430
PMCPMC10338913
OpenAlexW4382724389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.