Evidence map›Paper›PMID 37457306›Full record

ArticleHardwareX2023

Arduino based intra-cerebral microinjector device for neuroscience research.

Jorge Bravo-Martínez, Sonia Ortega-Tinoco, Julieta Garduño, Salvador Hernández-López

Open access · goldAbstract read
In one paragraph

Article in HardwareX, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jorge Bravo-MartínezDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), PO Box 70250, Ciudad de México 04510, Mexico.
Sonia Ortega-TinocoDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), PO Box 70250, Ciudad de México 04510, Mexico.
Julieta GarduñoDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), PO Box 70250, Ciudad de México 04510, Mexico.
Salvador Hernández-LópezDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), PO Box 70250, Ciudad de México 04510, Mexico.
Universidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotaxic surgery is a less invasive form of surgery that uses a three-dimensional coordinate system to place instruments at a specific location in the brain. Through this type of surgery, one can place needles among other tools within the structures of the brain. Therefore, injections can be given in order to deliver substances that cannot cross the blood-brain barrier. The two most important parameters of the microinjection to control are volume and speed. The volume should not be so large that it displaces the brain tissue and tears it. The injection speed must also be slow so that the liquid that comes out of the syringe can diffuse into the tissue without displacing it and damaging it. Thus, the objectives of the present work are: 1) To develop not a 3D printed prototype but an end-user device. 2) The device must be for animal research only. 3) It must have the same precision in volume and speed as commercial devices. 4) It must be adjustable for microsyringes from 0.5 µl to 1 ml. 5) It must be possible to place it directly on the stereotaxic surgery apparatus and to use it separately. 6) The price must be substantially lower than that of the commercial devices.

Indexed as

ArduinoIntracerebral injectionMicroinjectionNeuroscienceOpen hardwareStereotaxic surgery

Identifiers

PMID37457306
PMCPMC10344678
OpenAlexW4382196173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.