Evidence map›Paper›PMID 37457054›Full record

ArticleEuropean heart journal. Case reports2023

Unloading, ablation, bridging and transplant: different indications and treatments using the Impella 5.5 as longer-term circulatory support in one patient-an interdisciplinary case report.

Constanze Volgmann, Markus J Barten, Yousuf Al Assar, Hanno Grahn, Andreas Metzner, Gerold Söffker, Leonie Schulte-Uentrop, Christina Magnussen, Paulus Kirchhof, Stefan Kluge and 4 more

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Constanze VolgmannDepartment of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Martinistrasse 52, 20246 Hamburg.ORCID https://orcid.org/0000-0001-6706-4015
Markus J BartenDepartment of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Martinistrasse 52, 20246 Hamburg.
Yousuf Al AssarDepartment of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Martinistrasse 52, 20246 Hamburg.
Hanno GrahnDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.
Andreas MetznerDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.
Gerold SöffkerDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.
Leonie Schulte-UentropDepartment of Anesthesiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Christina MagnussenDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.ORCID https://orcid.org/0000-0002-5102-0955
Paulus KirchhofDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.ORCID https://orcid.org/0000-0002-1881-0197
Stefan KlugeDepartment of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Susanne DollDepartment of Cardiovascular Surgery, Schüchtermann Clinic, Bad Rothenfelde, Germany.
Nicolas DollDepartment of Cardiovascular Surgery, Schüchtermann Clinic, Bad Rothenfelde, Germany.
Hermann ReichenspurnerDepartment of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Martinistrasse 52, 20246 Hamburg.
Alexander M BernhardtDepartment of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Martinistrasse 52, 20246 Hamburg.ORCID https://orcid.org/0000-0001-9974-8091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In patients with cardiogenic shock the clinical treatment often involves temporary mechanical circulatory support for initial haemodynamic stabilization to enable further assessment of therapeutic strategies. The surgically implanted Impella 5.5 can be used for several indications like ventricular unloading, haemodynamic support during high-risk interventions, and as a bridge-to-transplant strategy.We present an interdisciplinary managed case of using Impella 5.5 for multiple indications and treatment strategies in one patient. Case summary: A 66-year-old patient with known dilated cardiomyopathy was admitted with non-ST-elevation myocardial infarction and underwent urgent coronary bypass grafting. His native heart function did not recover and he experienced recurrent episodes of sustained ventricular tachycardia (VT) and electrical storm. He was evaluated for heart transplantation (OHT) and received a VT-ablation. However, he suffered an in-hospital cardiac arrest (IHCA) with subsequent implantation of an extracorporeal life support system (ECLS). After surgical placement of an Impella 5.5 due to left ventricular distension and pulmonary congestion, the ECLS was successfully weaned. He showed good neurological outcomes and underwent another high-risk VT-ablation. The patient was further stabilized under Impella 5.5 support in a bridge-to-transplant strategy. After 34 days he underwent a successful OHT. Discussion: In this interdisciplinary case report the surgically implanted Impella 5.5 as temporary mechanical circulatory support was used for multiple different indications and treatment strategies like ventricular unloading, haemodynamic support during high-risk interventions, and as bridge-to-transplant strategy in one patient.

Indexed as

Bridge to heart transplantationCardiac unloadingCase reportMechanical circulatory supportVT ablation

Identifiers

PMID37457054
PMCPMC10349291

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.