Evidence map›Paper›PMID 37456971›Full record

ArticleWorld journal of methodology2023

Microvessel density in patients with gastrointestinal stromal tumors: A systematic review and meta-analysis.

Konstantinos Perivoliotis, Ioannis Baloyiannis, Athina A Samara, Prodromos Koutoukoglou, Panagiotis Ntellas, Katerina Dadouli, Maria Ioannou, Konstantinos Tepetes

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of methodology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Konstantinos PerivoliotisDepartment of Surgery, University Hospital of Larissa, Larissa 41110, Greece.
Ioannis BaloyiannisDepartment of Surgery, University Hospital of Larissa, Larissa 41110, Greece.
Athina A SamaraDepartment of Surgery, University Hospital of Larissa, Larissa 41110, Greece. at.samara93@gmail.com.
Prodromos KoutoukoglouResearch Methodology in Biomedicine, Biostatistics and Clinical Bioinformatics, University of Thessaly, 41110 41110, Greece.
Panagiotis NtellasDepartment of Pathology, University Hospital of Larissa, Larissa 41110, Greece.
Katerina DadouliResearch Methodology in Biomedicine, Biostatistics and Clinical Bioinformatics, University of Thessaly, 41110 41110, Greece.
Maria IoannouDepartment of Pathology, University Hospital of Larissa, Larissa 41110, Greece.
Konstantinos TepetesDepartment of Surgery, University Hospital of Larissa, Larissa 41110, Greece.
University Hospital of Larissa · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal stromal tumors (GISTs) are considered the most common mesenchymal tumors of the gastrointestinal tract. Microvessel density (MVD) constitutes a direct method of vascularity quantification and has been associated with survival rates in multiple malignancies.

aimTo appraise the effect of MVD on the survival of patients with GIST.

methodsThis study adhered to Systematic reviews and Meta-Analyses guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. Electronic scholar databases and grey literature repositories were systematically screened. The Fixed Effects or Random Effects models were used according to the Cochran Q test.

resultsIn total, 6 eligible studies were identified. The pooled hazard ratio (HR) for disease free survival (DFS) was 8.52 (95%CI: 1.69-42.84,

conclusionMVD significantly correlates with the HR of DFS and overall survival rates at 36 and 120 mo. Further prospective studies of higher methodological quality are required.

Indexed as

Gastrointestinal stromalMeta-analysisMicrovessel densitySurvivalVascularity

Identifiers

PMID37456971
PMCPMC10348082
OpenAlexW4381145184

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.