Evidence map›Paper›PMID 37456833›Full record

ArticleiScience2023

Wet adhesive hydrogels to correct malacic trachea (tracheomalacia)

Ece Uslu, Vijay Kumar Rana, Sokratis Anagnostopoulos, Peyman Karami, Alessandra Bergadano, Cecile Courbon, Francois Gorostidi, Kishore Sandu, Nikolaos Stergiopulos, Dominique P Pioletti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ece UsluLaboratory of Biomechanical Orthopedics, Institute of Bioengineering, School of Engineering, EPFL, Lausanne, Switzerland.
Vijay Kumar RanaLaboratory of Biomechanical Orthopedics, Institute of Bioengineering, School of Engineering, EPFL, Lausanne, Switzerland.
Sokratis AnagnostopoulosLaboratory of Hemodynamics and Cardiovascular Technology, Institute of Bioengineering, School of Engineering, EPFL, Lausanne, Switzerland.
Peyman KaramiLaboratory of Biomechanical Orthopedics, Institute of Bioengineering, School of Engineering, EPFL, Lausanne, Switzerland.
Alessandra BergadanoVeterinary College, Bern, Switzerland.
Cecile CourbonDepartment of Anesthesiology, University Hospital, CHUV, Lausanne, Switzerland.
Francois GorostidiDepartment of Otorhinolaryngology, Airway Sector, University Hospital, CHUV, Lausanne, Switzerland.
Kishore SanduDepartment of Otorhinolaryngology, Airway Sector, University Hospital, CHUV, Lausanne, Switzerland.
Nikolaos StergiopulosLaboratory of Hemodynamics and Cardiovascular Technology, Institute of Bioengineering, School of Engineering, EPFL, Lausanne, Switzerland.
Dominique P PiolettiLaboratory of Biomechanical Orthopedics, Institute of Bioengineering, School of Engineering, EPFL, Lausanne, Switzerland.
École Polytechnique Fédérale de Lausanne · CHUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tracheomalacia (TM) is a condition characterized by a weak tracheal cartilage and/or muscle, resulting in excessive collapse of the airway in the newborns. Current treatments including tracheal reconstruction, tracheoplasty, endo- and extra-luminal stents have limitations. To address these limitations, this work proposes a new strategy by wrapping an adhesive hydrogel patch around a malacic trachea. Through a numerical model, first it was demonstrated that a hydrogel patch with sufficient mechanical and adhesion strength can preserve the trachea's physiological shape. Accordingly, a new hydrogel providing robust adhesion on wet tracheal surfaces was synthesized employing the hydroxyethyl acrylamide (HEAam) and polyethylene glycol methacrylate (PEGDMA) as main polymer network and crosslinker, respectively.

Indexed as

Applied sciencesBiomaterials

Identifiers

PMID37456833
PMCPMC10338288
OpenAlexW4381137015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.