ReviewFrontiers in bioengineering and biotechnology2023
Polyetheretherketone development in bone tissue engineering and orthopedic surgery.
Review in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
- Porous Ti-6Al-4V Architectures in Load-Bearing Orthopedic Reconstruction: A Critical Narrative Review of the Translational Gap Across Microstructure, Fatigue, Surface Function, and Clinical Failure Modes.Materials (Basel, Switzerland) · 2026Review
- PEEK in modern maxillofacial surgery: clinical applications, limitations and future opportunities.British dental journal · 2026Review
- From Concept to Clinic: Pre-Clinical Testing and Regulatory Considerations in Spine Implant Development.JOR spine · 2026Review
- Role of polyetheretherketone (PEEK) in arthroplasty and orthopaedics: a review of biomechanical properties, surface modifications, and clinical outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Review
- Near-Infrared Switch-Driven Macrophage Dynamically Reprogramming for Anti-Infection and Tissue Healing on Polyetheretherketone Implants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Review
- Evolution of Anchor Polymer Systems Used in Arthroscopic Shoulder Surgery-A Comprehensive Review.Bioengineering (Basel, Switzerland) · 2025Review
- CF-PEEK vs. Titanium Dental Implants: Stress Distribution and Fatigue Performance in Variable Bone Qualities.Biomimetics (Basel, Switzerland) · 2025Article
- The Use of Non-Degradable Polymer (Polyetheretherketone) in Personalized Orthopedics-Review Article.Polymers · 2025Review
- Advancements in Nanotechnology for Spinal Surgery: Innovations in Spinal Fixation Devices for Enhanced Biomechanical Performance and Osteointegration.Nanomaterials (Basel, Switzerland) · 2025Review
- Revolutionizing Dental Polymers: The Versatility and Future Potential of Polyetheretherketone in Restorative Dentistry.Polymers · 2024Review
- Surface modification of PEEK implants for craniofacial reconstruction and aesthetic augmentation-fiction or reality?Frontiers in surgery · 2024Review
- Performance of 3D printed porous polyetheretherketone composite scaffolds combined with nano-hydroxyapatite/carbon fiber in bone tissue engineering: a biological evaluation.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyetheretherketone (PEEK) has been widely used in the medical field as an implant material, especially in bone tissue engineering and orthopedic surgery, in recent years. This material exhibits superior stability at high temperatures and is biosecured without harmful reactions. However, the chemical and biological inertness of PEEK still limits its applications. Recently, many approaches have been applied to improve its performance, including the modulation of physical morphology, chemical composition and antimicrobial agents, which advanced the osteointegration as well as antibacterial properties of PEEK materials. Based on the evolution of PEEK biomedical devices, many studies on the use of PEEK implants in spine surgery, joint surgery and trauma repair have been performed in the past few years, in most of which PEEK implants show better outcomes than traditional metal implants. This paper summarizes recent studies on the modification and application of biomedical PEEK materials, which provides further research directions for PEEK implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.