Evidence map›Paper›PMID 37456451›Full record

ArticleCureus2023

Acute Graft Versus Host Disease After Kidney-Pancreas Transplant.

James Lopez, Vishal Devarkonda, Moe Thuzar, Roberto Silva, Hugo Akabane

Abstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James LopezHematology and Medical Oncology, Louisiana State University Health Sciences Center, Shreveport, USA.
Vishal DevarkondaInternal Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Moe ThuzarInternal Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Roberto SilvaPathology, Louisiana State University Health Sciences Center, Shreveport, USA.
Hugo AkabaneHematology and Medical Oncology, Louisiana State University Health Sciences Center, Shreveport, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute graft vs. host disease (aGVHD) results from newly transplanted donor immune cells recognizing recipient tissues as foreign, leading to end-organ damage. Diagnosing aGVHD typically involves a combination of clinical evaluation, histological examination, laboratory tests, and imaging studies. Although typically associated with allogeneic stem cells transplant and less frequently with liver or small bowel transplants, solid organ transplant GVHD (SOT-GVHD) associated with kidney-pancreas transplants is exceedingly rare. Our patient presented with pancytopenia unexplained by typical causes. He developed classical aGVHD findings of fever, diarrhea, rash, and abnormal liver tests. Our case underscores the importance of keeping a broad differential when evaluating solid organ transplant patients.

Indexed as

acute graft vs host diseasegraftsolid organ transplanttransplantunexplained shock

Identifiers

PMID37456451
PMCPMC10348074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.