Evidence map›Paper›PMID 37456376›Full record

ArticleCureus2023

A Cytological Study of Oral Human Papillomavirus (HPV) Infection Among Electronic Cigarette Smokers in Al-Madinah Al-Munawara.

Faris M Elmahdi, Razan S Aljohani, Nouf A Alharbi, Sama E Yousef, Noor M Alharbi, Reema B Afasha, Rawan B Aljohani, Yara K Alhejaili, Nasser O Almuzaini

Abstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Toxicological Effects of e-Cigarette Use in the Upper Airway: A Scoping Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Faris M ElmahdiCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Razan S AljohaniCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Nouf A AlharbiCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Sama E YousefCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Noor M AlharbiCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Reema B AfashaCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Rawan B AljohaniCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Yara K AlhejailiCollege of Medicine, Al-Rayan Colleges, Madinah, SAU.
Nasser O AlmuzainiInternal Medicine, Meqat General Hospital, Madinah, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective This study aims to determine how electronic cigarette (e-cigarette) use contributes to the spread of the human papillomavirus (HPV) and to assess the potential cellular proliferative activity it may produce. Methodology In Madinah, a case-control study was conducted between October 2022 and March 2023. Two oral cytologic smear samples were collected from each of the 500 volunteers; 250 consumers of electronic cigarettes and 250 non-smokers each provided two samples. To detect cytological changes and HPV infection, these samples were stained using Papanicolaou and immunocytochemical techniques. Results Twelve (4.8%) of the electronic cigarettes exhibited cytological atypia, while only one (0.4%) of the nonsmokers' group did. Infection with the human papillomavirus (HPV) was detected in eight (3.2%) of the e-cigarette users, but it was only found in two (0.8%) of the nonsmokers (P ≤ 0.05). Conclusion Electronic cigarette smoking increases the likelihood of contracting HPV and developing cytological atypia, both of which, if left untreated, can contribute to the development of precancerous and cancerous lesions in the mouth.

Indexed as

al-madinahcytological atypiaelectronic cigarettehpvoral cancer

Identifiers

PMID37456376
PMCPMC10348396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.