Evidence map›Paper›PMID 37456245›Full record

ArticleFrontiers in oncology2023

Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain.

Ashley Sunderland, Jennifer Williams, Tereza Andreou, Nora Rippaus, Christopher Fife, Fiona James, Yolanda Dyah Kartika, Valerie Speirs, Ian Carr, Alastair Droop and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

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  9. Metabolic adaptations of brain metastasis.Nature reviews. Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ashley SunderlandSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Jennifer WilliamsSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Tereza AndreouSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Nora RippausSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Christopher FifeSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Fiona JamesSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Yolanda Dyah KartikaSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Valerie SpeirsSchool of Medicine, Medical Science and Nutrition, University of Aberdeen, Aberdeen, United Kingdom.
Ian CarrSchool of Medicine, University of Leeds, Leeds, United Kingdom.
Alastair DroopExperimental Cancer Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom.
Mihaela LorgerSchool of Medicine, University of Leeds, Leeds, United Kingdom.
University of Leeds · GBUniversity of Aberdeen · GBWellcome Sanger Institute · GB

Funding

Medical Research Council MR/S002057/1Medical Research Council MR/V029843/1
6 · The paper itself

Abstract

Exit of quiescent disseminated cancer cells from dormancy is thought to be responsible for metastatic relapse and a better understanding of dormancy could pave the way for novel therapeutic approaches. We used an

Indexed as

biglycanbrain metastasesbreast cancerdormancyglycolysisYAP

Identifiers

PMID37456245
PMCPMC10339804
OpenAlexW4382722958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.