Evidence map›Paper›PMID 37455905›Full record

ArticleFrontiers in endocrinology2023

The comparison of three different molecular imaging methods in localization and grading of insulinoma.

Lina Chang, Xinyu Bi, Shuo Li, Qi Tong, Yian Gu, Zonghao He, Yansheng Li, Qiusong Chen, Jingqiu Cui, Haonan Yu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Glucagon-like peptide-1 receptor PET/CT withEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Lina ChangDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Xinyu BiDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Shuo LiDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Qi TongDepartment of General Internal Medicine, Baodi District People's Hospital, Tianjin, China.
Yian GuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Zonghao HeDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Yansheng LiDepartment of PET/CT Examination Room, Tianjin Medical University General Hospital, Tianjin, China.
Qiusong ChenDepartment of PET/CT Examination Room, Tianjin Medical University General Hospital, Tianjin, China.
Jingqiu CuiDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Haonan YuDepartment of PET/CT Examination Room, Tianjin Medical University General Hospital, Tianjin, China.
Qing HeDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Ming LiuDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: This cross-sectional study compared the value of molecular imaging (Exendin-4 positron emission tomography/computed tomography [PET/CT], Methods: In 28 insulinoma patients, the sensitivity of three types of PET/CT for localizing insulinoma was calculated according to tumor size and grade. We compared the SUVmax for different insulinoma grades and analyzed the correlation of SUVmax with Ki-67, maximum tumor diameter, and glucose metabolism indicators. Results: The study included 12 grade (G) 1 and 16 G2 cases, with maximum tumor diameters ranging from 9 to 40 mm. Without differentiation by size and grade, the sensitivity of Exendin-4 PET/CT to localize insulinoma was 100%, which significantly exceeded that of Conclusion: Exendin-4 PET/CT was superior to

Indexed as

InsulinomaNeuroendocrine TumorsPancreatic NeoplasmsCross-Sectional StudiesExenatideFluorodeoxyglucose F18Gallium RadioisotopesGlucoseHumansKi-67 AntigenMolecular ImagingExenatideFluorodeoxyglucose F18Gallium RadioisotopesGlucoseKi-67 AntigengradeinsulinomaKi-67maximum standardized uptake valuemolecular imagingpositron emission tomography/computed tomography (PET/CT)

Identifiers

PMID37455905
PMCPMC10348808
OpenAlexW4382656962

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.