Evidence map›Paper›PMID 37455601›Full record

ArticleBiomaterials science2023

Thermosensitive biomaterial gels with chemical permeation enhancers for enhanced microneedle delivery of naltrexone for managing opioid and alcohol dependency.

Kevin V Tobin, Nicole K Brogden

Open access · hybridAbstract read
In one paragraph

Article in Biomaterials science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Rethinking asthma therapy, part 2: transdermal strategies for adjunct asthma and allergy treatments.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2026
    Review
  5. Review
  6. Article
  7. Study of the effect of active pharmaceutical ingredients of various classes of BCS on the parameters of thermosensitive systems based on poloxamers.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kevin V TobinDepartment of Pharmaceutical Sciences and Experimental Therapeutics, The University of Iowa College of Pharmacy, Iowa City, IA 52242, USA. nicole-brogden@uiowa.edu.
Nicole K BrogdenDepartment of Pharmaceutical Sciences and Experimental Therapeutics, The University of Iowa College of Pharmacy, Iowa City, IA 52242, USA. nicole-brogden@uiowa.edu.ORCID http://orcid.org/0000-0001-6838-8847
University of Iowa · US

Funding

The effects of pharmacologic and physiologic variables on the pharmacokinetics of microneedle drug deliveryR35GM124551 · NIGMS · UNIVERSITY OF IOWA · PI BROGDEN, NICOLE K · 2017 to 2021
$2.1M
NIGMS NIH HHS R35 GM124551
6 · The paper itself

Abstract

Naltrexone (NTX) can be transdermally delivered using microneedles (MN) to treat opioid and alcohol misuse disorders, but delivery is blunted by rapid

Indexed as

AlcoholismNaltrexoneAnalgesics, OpioidAnimalsBenzyl AlcoholsDimethyl SulfoxideDrug Delivery SystemsGelsHumansPoloxamerSkin AbsorptionSwineAnalgesics, OpioidBenzyl AlcoholsDimethyl SulfoxideGelsNaltrexonePoloxamer

Identifiers

PMID37455601
PMCPMC10443048
OpenAlexW4384493043

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.