Evidence map›Paper›PMID 37455501›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2023

Treatment of a ruptured shallow trilobed cerebral aneurysm with the novel saccular endovascular aneurysm lattice (SEAL) device: A case report with one year follow-up.

Boris Pabon, Victor Torres, Keith Woodward, Margarita Cardozo, Benedict Tan, Varun Chaubal, Aamir Badruddin, Thomas Wolfe, Edgard Pereira, Brian Jankowitz and 4 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Endovascular treatment of a symptomatic giant partially thrombosed aneurysm with saccular endovascular aneurysm lattice (SEAL) XL: The world's largest novel intrasaccular device.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Review
  5. Review
  6. Frontiers in neurology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Boris PabonDepartment of Neurosurgery, Universidad De Antioquia, Medellin, Colombia.
Victor TorresDepartment of Neurosurgery, Universidad De Antioquia, Medellin, Colombia.
Keith WoodwardDepartment of Neurointerventional Radiology, Covenant Health, Knoxville, TN, USA.
Margarita CardozoDepartment of Neurosurgery, Universidad De Antioquia, Medellin, Colombia.
Benedict TanDepartment of Neurosciences, St. Vincent Mercy Medical Center, Toledo, OH, USA.ORCID 0000-0001-7485-7283
Varun ChaubalDepartment of Neurosciences, St. Vincent Mercy Medical Center, Toledo, OH, USA.ORCID 0009-0003-5354-1636
Aamir BadruddinGalaxy Therapeutics INC, Milpitas, CA, USA.
Thomas WolfeGalaxy Therapeutics INC, Milpitas, CA, USA.
Edgard PereiraGalaxy Therapeutics INC, Milpitas, CA, USA.
Brian JankowitzDepartment of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Vincent CostalatDepartment of Neuroradiology, Gui de Chauliac University Hospital of Montpellier, Montpellier, France.
David AltschulDepartment of Neurosurgery, Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0002-5130-1378
Claire A LangerfordMedX CRO, Toledo, OH, USA.
Osama O ZaidatGalaxy Therapeutics INC, Milpitas, CA, USA.
Galaxy Diagnostics (United States) · USUniversidad de Antioquia · COMercy St. Vincent Medical Center · USAlbert Einstein College of Medicine · USCentre Hospitalier Universitaire de Montpellier · FRUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrasaccular flow disruption is a viable alternative to other endovascular treatments for saccular or wide-necked bifurcation intracranial aneurysms; however, wide neck aneurysms with irregular shapes or shallow depth may not be amenable to treatment currently available intrasaccular devices. Here, we present the first ever case report of the novel Saccular Endovascular Aneurysm Lattice Embolization System (SEAL™). The versatile utility of the SEAL™ device is demonstrated in a patient with acute subarachnoid hemorrhage (SAH) from a ruptured, complex, left middle cerebral artery (MCA) trilobed shallow wide-necked bifurcation aneurysm. Deployment and implantation of the SEAL device were technically feasible, safe, and conformed well to the irregular shape of the complex, ruptured aneurysm. Immediate total aneurysm occlusion was observed after implantation. Importantly, 1-year angiographic follow-up demonstrated durable, complete occlusion with no safety concerns. The SEAL device is a promising new novel technology which has the potential to treat very shallow aneurysms with limited height and irregular, multilobulated aneurysms.

Indexed as

Aneurysm, RupturedAortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmCerebral AngiographyFollow-Up StudiesHumansRetrospective StudiesTreatment Outcomeaneurysmendovascularflow diversionruptureSaccular

Identifiers

PMID37455501
PMCPMC10399503
OpenAlexW4384493101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.