Evidence map›Paper›PMID 37455231›Full record

ArticleUrologic oncology2023

Determining the association of rurality and cardiovascular disease among prostate cancer survivors.

Shaelee Nielsen, Brock O'Neil, Chun-Pin Chang, Bayarmaa Mark, John Snyder, Vikrant Deshmukh, Michael Newman, Ankita Date, Carlos Galvao, N Lynn Henry and 2 more

2 registry-linked trialsOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07032584 narecruitingnot on this mapstarted 2025, after this paper: background citation

Impact of Multimodal Telerehabilitation on Reducing Disparities in Rural Survivors of Metastatic Prostate Cancer

TypeinterventionalSponsorUniversity of UtahRan2025 to 2029Enrolled74ConditionsProstate Cancer, Metastatic Prostate Cancer, Androgen Deprivation TherapyArmsTelerehabilitation Intervention
NCT07093177 narecruitingnot on this mapstarted 2026, after this paper: background citation

Multimodal Telerehabilitation of Rural Patients With Advanced Prostate Cancer

TypeinterventionalSponsorUniversity of UtahRan2026 to 2028Enrolled30ConditionsProstate CancerArmsTelerehabilitation Unit
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Risks of adverse health outcomes among older rural prostate cancer survivors in the SEER-Medicare data.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Shaelee NielsenDivision of Urology, University of Utah, Salt Lake City, UT.
Brock O'NeilDivision of Urology, University of Utah, Salt Lake City, UT. Electronic address: brock.oneil@hci.utah.edu.
Chun-Pin ChangDepartment of Family and Preventative Medicine, University of Utah, Salt Lake City, UT.
Bayarmaa MarkDepartment of Family and Preventative Medicine, University of Utah, Salt Lake City, UT.
John SnyderIntermountain Healthcare, Salt Lake City, UT.
Vikrant DeshmukhDepartment of Health Sciences, University of Utah, Salt Lake City, UT.
Michael NewmanDepartment of Health Sciences, University of Utah, Salt Lake City, UT.
Ankita DatePedigree and Population Resource, Population Sciences, Huntsman Cancer Institute, Salt Lake City, UT.
Carlos GalvaoPedigree and Population Resource, Population Sciences, Huntsman Cancer Institute, Salt Lake City, UT.
N Lynn HenryDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI.
Shane LloydDepartment of Radiation Oncology, University of Utah, Salt Lake City, UT.
Mia HashibeDepartment of Family and Preventative Medicine, University of Utah, Salt Lake City, UT.
University of Utah · USHuntsman Cancer Institute · USIntermountain Healthcare · USUniversity of Michigan–Ann Arbor · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI KATHARINE S ULLMAN · 1986 to 2026
$72.6M
Long-Term Adverse Outcomes Among Rural Cancer Survivors in a Population-Based CohortR01CA244326 · NCI · UNIVERSITY OF UTAH · PI CAMP, NICOLA J., HASHIBE, MIA · 2020 to 2024
$2.4M
Sharing statewide health data for genetic research (1 R01 RR021746-01A1)R01RR021746 · NCRR · UNIVERSITY OF UTAH · PI MINEAU, GERALDINE P · 2007 to 2009
$770k
NCI NIH HHS HHSN261201800016CNCI NIH HHS HHSN261201800016INCI NIH HHS P30 CA042014NCI NIH HHS R01 CA244326NCRR NIH HHS R01 RR021746
6 · The paper itself

Abstract

purposeRural disparities in prostate cancer survivorship and cardiovascular disease remain. Prostate cancer treatment also contributes to worse cardiovascular disease outcomes. Our objective was to determine whether rural-urban differences in cardiovascular outcomes contribute to disparities in prostate cancer survivorship. MATERIALS AND

methodsData were collected from the Utah Population Database. Rural and urban prostate cancer survivors were matched by diagnosis year and age. Cox proportional hazards models were used to estimate hazard ratios for cardiovascular disease (levels 1-3) based on rural-urban classification, while controlling for demographic and socioeconomic characteristics. We identified 3,379 rural and 16,253 urban prostate cancer survivors with a median follow-up of 9.3 years.

resultsResults revealed that rural survivors had a lower risk of hypertension (HR 0.90), diseases of arteries (HR 0.92), and veins (HR 0.92) but a higher risk of congestive heart failure (HR 1.17). Interactions between level 2 cardiovascular diseases and rural/urban status, showed that diseases of the heart had a distinct between-group relationship for all-cause (P = 0.005) and cancer-specific mortality (P = 0.008).

conclusionsThis study revealed complex relationships between rural-urban status, cardiovascular disease, and prostate cancer. Rural survivors were less likely to be diagnosed with screen-detected cardiovascular disease but more likely to have heart failure. Further, the relationship between cardiovascular disease and survival was different between rural and urban survivors. It may be that our findings underscore differences in healthcare access where rural patients are less likely to be screened for preventable cardiovascular disease and have worse outcomes when they have a major cardiovascular event.

Indexed as

Cancer SurvivorsCardiovascular DiseasesProstatic NeoplasmsHumansMaleProstateSurvivorsUrban PopulationAccessibility of health servicesCardiovascular diseaseProstate cancerRural populationSocioeconomic status

Identifiers

PMID37455231
PMCPMC10787808
OpenAlexW4384470689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.