Evidence map›Paper›PMID 37455229›Full record

ArticleZeitschrift fur medizinische Physik2025

Evaluation of proton and carbon ion beam models in TReatment Planning for Particles 4D (TRiP4D) referring to a commercial treatment planning system.

Yinxiangzi Sheng, Lennart Volz, Weiwei Wang, Marco Durante, Christian Graeff

Open access · goldAbstract read
In one paragraph

Article in Zeitschrift fur medizinische Physik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yinxiangzi ShengBiophysics GSI Helmholtz Center for Heavy Ion Research GmbH, Darmstadt, Germany; Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai, China; School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.
Lennart VolzBiophysics GSI Helmholtz Center for Heavy Ion Research GmbH, Darmstadt, Germany.
Weiwei WangDepartment of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Marco DuranteBiophysics GSI Helmholtz Center for Heavy Ion Research GmbH, Darmstadt, Germany; Institute of Condensed Matter Physics, Technical University of Darmstadt, Darmstadt, Germany.
Christian GraeffBiophysics GSI Helmholtz Center for Heavy Ion Research GmbH, Darmstadt, Germany; Institute of Electrical Engineering and Information Technology, Technical University of Darmstadt, Darmstadt, Germany. Electronic address: c.graeff@gsi.de.
GSI Helmholtz Centre for Heavy Ion Research · DEShanghai Jiao Tong University · CNTechnical University of Darmstadt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the accuracy of the treatment planning system (TPS) TRiP4D in reproducing doses computed by the clinically used TPS SyngoRT.

methodsProton and carbon ion beam models in TRiP4D were converted from SyngoRT. Cubic plans with different depths in a water-tank phantom (WP) and previously treated and experimentally verified patient plans from SyngoRT were recalculated in TRiP4D. The target mean dose deviation (ΔD

resultsThe carbon and proton absorbed dose gamma passing rates (γ-PRs) were ≥99.93% and ΔD

conclusionThe absorbed dose between TRiP4D and SyngoRT were identical for both proton and carbon ion plans in the WP. Compared to SyngoRT, TRiP4D underestimated the target RBE-weighted dose; however more efficient in RBE-weighted dose calculation. Large variation for proton beam with range shifter was observed. TRiP4D will be used to evaluate doses delivered to moving targets. Uncertainties inherent to the 4D-dose reconstruction calculation are expected to be significantly larger than the dose errors reported here. For this reason, the residual differences between TRiP4D and SyngoRT observed in this study are considered acceptable. The study was approved by the Institutional Research Board of Shanghai Proton and Heavy Ion Center (approval number SPHIC-MP-2020-04, RS).

Indexed as

CarbonHeavy Ion RadiotherapyProton TherapyRadiotherapy Planning, Computer-AssistedHumansPhantoms, ImagingRadiotherapy DosageCarbondosimetric comparisonparticle radiotherapytreatment planning

Identifiers

PMID37455229
PMCPMC12166908
OpenAlexW4384344084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.