Evidence map›Paper›PMID 37454733›Full record

Trial reportJournal of substance use and addiction treatment2023

A randomized control trial of a combined community health worker and re-entry intervention for people with HIV recently released from jail who use substances.

Emily Hoff, Laura Hansen, Zoe Pulitzer, Nicholas Campalans, Maverick Salyards, Maishara Muquith, Shira Shavit, Hue Nguyen, Christina Crain, Robrina Walker and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance use and addiction treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Emily HoffDepartment of Internal Medicine, University of Texas-Southwestern, Dallas, TX, United States.
Laura HansenDivision of Infectious Diseases and Geographic Medicine, University of Texas-Southwestern, Dallas, TX, United States.
Zoe PulitzerDivision of Infectious Diseases and Geographic Medicine, University of Texas-Southwestern, Dallas, TX, United States.
Nicholas CampalansDepartment of Internal Medicine, University of California San Francisco, San Francisco, CA, United States.
Maverick SalyardsDivision of Infectious Diseases and Geographic Medicine, University of Texas-Southwestern, Dallas, TX, United States; Department of Public Health, Texas Christian University, United States.
Maishara MuquithDepartment of Internal Medicine, University of Texas-Southwestern, Dallas, TX, United States.
Shira ShavitDepartment of Family and Community Medicine, University of California San Francisco, San Francisco, CA, United States.
Hue NguyenUnlocking DOORS®, Dallas, TX, United States.
Christina CrainUnlocking DOORS®, Dallas, TX, United States.
Robrina WalkerDivision of Infectious Diseases and Geographic Medicine, University of Texas-Southwestern, Dallas, TX, United States; The Emmes Company, Rockville, MD, United States.
Ank E NijhawanDepartment of Internal Medicine, University of Texas-Southwestern, Dallas, TX, United States; Division of Infectious Diseases and Geographic Medicine, University of Texas-Southwestern, Dallas, TX, United States. Electronic address: ank.nijhawan@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · USUniversity of California, San Francisco · USTexas Christian University · US

Funding

NORTH AND CENTRAL TEXAS CTSA FOR PEDIATRIC RESEARCHUL1RR024982 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$27.9M
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
A Community-Clinic Collaboration to Improve Outcomes in HIV+ Substance Users Released from JailR34DA045592 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI NIJHAWAN, ANK ELISABETH · 2018 to 2020
$729k
NCATS NIH HHS UL1 TR001105NCRR NIH HHS UL1 RR024982NIDA NIH HHS R34 DA045592
6 · The paper itself

Abstract

introductionPeople with human immunodeficiency virus (HIV; PWH) who use substances are disproportionately involved in the criminal justice system. While HIV viral suppression typically improves during incarceration, these gains are frequently lost after release. We evaluated the impact of a combined intervention (formerly incarcerated community health workers [CHW] plus a re-entry organization; CHW+) on postrelease HIV- and substance use-related outcomes.

methodsWe conducted a pilot randomized controlled trial of a CHW+ for PWH who use substances, within 30 days of release from a large southern, urban jail. Between February 2019 and August 2021, participants were recruited, enrolled, and randomized to treatment as usual (TAU; passive referral to care) or CHW+. Follow up study visits occurred at 3, 6, and 12 months. The primary outcome was HIV VL at 6 months; secondary outcomes included 6-month urinary toxicology and high-risk substance use at 12 months.

resultsA total of 31 participants were enrolled who were primarily male (n = 24; 77 %), Black (n = 22; 71 %), unemployed (n = 23; 74.2 %), had unstable housing (n = 18; 58 %), had food insecurity (n = 14; 45 %), and reported their drug of choice was stimulants (n = 24; 77 %). The study identified no significant difference in HIV VL suppression at 6 months (20 % v. 37 %; [CHW+ v. TAU], p = 0.61). We observed improved substance use outcomes in CHW+ v. TAU, including fewer positive urinary toxicology screens for stimulants (40 % v. 100 %; p = 0.01) and a trend toward less high-risk substance use (30 % v. 43 %). The CHW+ group met more basic needs, such as food security [+32 % v. +11 %], housing security [+52 % v. -7 %] and full-time employment [+20 % v. +5 %] compared to TAU.

conclusionsPWH who use substances assigned to a combined intervention of CHW+ after jail release did not achieve higher rates of HIV VL suppression than TAU; however, they had improved substance use outcomes and met more basic subsistence needs. Results highlight the potential of culturally informed interventions to address the competing needs of PWH who use substances after release from jail and call for further development of innovative solutions to successfully bridge to HIV care in the community.

Indexed as

Central Nervous System StimulantsHIV InfectionsSubstance-Related DisordersCommunity Health WorkersFollow-Up StudiesHIVHumansJailsMaleCentral Nervous System StimulantsCommunity health workerCriminal justiceHIVSubstance use

Identifiers

PMID37454733
PMCPMC13552543
OpenAlexW4384461018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.