Evidence map›Paper›PMID 37454267›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2023

Effectiveness of acupoint application of Xiaozhong Zhitong Tie on diarrhea in patients: a retrospective cohort study in China.

Sheng Song, Zhang Yanhong, Gao Hongyang, M A Hangkun, Huang Ye, L I Qingna, Gao Rui, X U Fengqin

Abstract readMulticenter Study
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sheng SongEmergency Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Zhang YanhongEmergency Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Gao HongyangEmergency Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
M A HangkunEmergency Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Huang YeEmergency Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
L I QingnaInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Gao RuiInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
X U FengqinInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.

Funding

Major Science and Technology Innovation Project of China Academy of Chinese Medical Sciences: Research on the Key Techniques of Clinical Evaluation of New Chinese Medicine under the System of Three-in-one Combination Evidence Review CI2021A04701
6 · The paper itself

Abstract

objectiveTo provide the evidence for the efficacy of acupoint application (AA) for patients with diarrhea in a real-world setting.

methodsThis study is a national multicenter retrospective cohort study. Our study consecutively collected outpatient medical records of patients with diarrhea from hundreds of primary hospitals nationwide registered in Chun Bo Wan Xiang cloud platform from 22nd August, 2020 to 5th November, 2020. The patients were divided into the treatment group and the control group according to patient's condition and willingness. The control group was treated with Western Medicine, oral Chinese Medicine decoction, or both. The treatment group was added with AA based on the control group. Multiple logistic regression was used to evaluate the independent efficacy of AA in diarrheal recovery on the 3rd, 7th, 14th and 28th day. As a next step, we also performed stratified analysis and likelihood ratio test (LRT). Sensitivity analyses included propensity score matching (PSM), four PSM-related analyses and E-value.

resultsThe treatment group showed better efficacy than the control group on the 14th and 28th day [the 14th day: = 1.58, 95% (1.15, 2.19), 0.005; the 28th day: = 2.03, 95% (1.43, 2.88), < 0.001]. No difference was observed in efficacy of AA for the treatment of diarrhea among the subgroups ( > 0.05). PSM-related analyses confirmed the efficacy of AA in diarrheal recovery. The findings are unlikely to be nullified by an unmeasured confounding variable according to the results of E-values.

conclusionsThe efficacy in the treatment group was significantly more improved than that in the control group on the 14th and 28th day.

Indexed as

Acupuncture PointsDiarrheaChinaHumansRetrospective StudiesTreatment Outcomeacupoint applicationdiarrheareal-world studyretrospective cohort studyXiaozhong Zhitong Tie

Identifiers

PMID37454267
PMCPMC10320451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.