Evidence map›Paper›PMID 37454264›Full record

Trial reportJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2023

Early intervention improves clinical responses to seasonal allergic rhinitis by stimulation in sphenopalatine ganglion (Xinwu acupoint).

Guo Yuhao, Huang Liangran, Zhang Lei, Yang Wei, Huang Lixia, Liu Wei, Fan Yuyan

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Guo YuhaoDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Huang LiangranDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Zhang LeiDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Yang WeiDepartment of Traditional Chinese Medicine, Beijing Tongren Hospital, Beijing 100005, China.
Huang LixiaDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Liu WeiDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Fan YuyanDepartment of Traditional Chinese Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Capital Medical University · CNBeijing Institute of Neurosurgery · CNBeijing Tian Tan Hospital · CN

Funding

Fundamental Research Funds of Chinese Medicine in Capital Medical University: Exploration of the Efficacy and Mechanism of Early Acupuncture Intervention in Seasonal Recurrent Rhinitis: a Randomized Clinical Study 16ZY03National Natural Science Foundation of China: Study on the "Metabolic Memory" Effect of eNOS in Glomerular Endothelial Cells and the Role and Mechanism of Astragaloside IV in the Early Stages of Diabetic Nephropathy 81774214
6 · The paper itself

Abstract

objectiveTo examine the efficacy of early intervention (4 weeks before pollen dispersal) with sphenopalatine ganglion (Xinwu acupoint) stimulation in patients with allergies after the onset of seasonal allergic rhinitis (SAR).

methodsThis is a prospective, randomized and unblinded half-open study. Forty-one SAR volunteers were randomly assigned to either the sphenopalatine ganglion (SPG) acupuncture plus supplementary acupuncture (SPG group) or the sham-SPG acupuncture plus supplementary acupuncture (SA group) stimulation 4 weeks before the onset of allergy season. The changes of the total nasal symptom score (TNSS) and the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) scores were measured on the first week in the onset of allergy season.

resultsFour patients dropped out due to local hematoma and pain in the SPG and SA groups. The remaining 37 patients continued through to the end of the trial. After early intervention 4 weeks before the onset of allergy season, the sneezing, nasal congestion and itchiness scores in the first week of onset time were significantly lower in the SPG group than in the SA group patients ( 0.001). The RQLQ score obtained at the onset of symptoms indicated that symptoms were more significantly ameliorated in the SPG group than in the SA group (0.001).

conclusionsThe results of this study confirmed that early intervention by sphenopalatine ganglion (Xinwu acupoint) stimulation can effectively improve the symptoms and the quality of SAR patients' daily lives.

Indexed as

Acupuncture TherapyRhinitis, AllergicRhinitis, Allergic, SeasonalAcupuncture PointsHumansProspective StudiesQuality of LifeTreatment Outcomeacupunctureearly interventionrhinitis, allergic, seasonalsphenopalatineXinwu acupoint

Identifiers

PMID37454264
PMCPMC10320438
OpenAlexW4384466927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.