ArticleNature communications2023
Cooperative microbial interactions drive spatial segregation in porous environments.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Performance of Nitrogen Removal and Biofilm-Associated Microbial Community in a Compact Marine Shrimp Recirculating Aquaculture System with MBBR.Microorganisms · 2026Article
- Microbial Interactions Shape Spatial Organisation and Transcriptional Responses in a Model Mixed-Species Biofilm.Microbial ecology · 2026Article
- Spatial characteristics of soil enzyme activity and bacterial diversity in Chinese egret habitat.Microbiology spectrum · 2026Article
- Spatial structure: shaping the ecology and evolution of microbial communities.FEMS microbiology reviews · 2026Review
- Exploring cooperation among social pathogens: a computational perspective.FEMS microbiology reviews · 2026Review
- Linking spatial drug heterogeneity to microbial growth dynamics in theory and experiment.PLoS computational biology · 2026Article
- Simultaneous real-time imaging of oxygen gradients and in vivo microbial community spatial organization in confined environments.ISME communications · 2026Article
- Defined Electrosynthetic Microbial Consortia Reveal Electron Transfer Modes Governing Acetate Production.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Biophysics of Bacterial Colonial Structures and the Occupancy of Microecological Spaces.Biology · 2025Review
- Hydrogel-based experimental models of the gastrointestinal tract.Microbiome · 2025Review
- Biophysical metabolic modeling of complex bacterial colony morphology.Cell systems · 2025Article
- Characteristic Functional Genera (CFG) Mediate Nitrogen Priming Effect in the Microbiome of Saline-Alkaline Farmland.Plants (Basel, Switzerland) · 2025Article
- The mitigation of spatial constraint in porous environments enhances biofilm phylogenetic and functional diversity.Microbiome · 2025Article
- Role of horizontal gene transfer and cooperation in rhizosphere microbiome assembly.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Review
- Plant exudates-driven microbiome recruitment and assembly facilitates plant health management.FEMS microbiology reviews · 2025Review
- Pore-scale mass transfer heterogeneity shapes nutrient accessibility and functional assembly in porous microbial ecosystems.The ISME journal · 2025Article
- Framework nucleic acid strategy enables closer microbial contact for programming short-range interaction.Science advances · 2024Article
- Linking spatial drug heterogeneity to microbial growth dynamics in theory and experiment.bioRxiv : the preprint server for biology · 2024Article
- Spatially structured exchange of metabolites enhances bacterial survival and resilience in biofilms.Nature communications · 2024Article
- Microbes in porous environments: from active interactions to emergent feedback.Biophysical reviews · 2024Review
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of microbial interactions and the underlying mechanisms that shape complex biofilm communities are poorly understood. Here we employ a microfluidic chip to represent porous subsurface environments and show that cooperative microbial interactions between free-living and biofilm-forming bacteria trigger active spatial segregation to promote their respective dominance in segregated microhabitats. During initial colonization, free-living and biofilm-forming microbes are segregated from the mixed planktonic inoculum to occupy the ambient fluid and grain surface. Contrary to spatial exclusion through competition, the active spatial segregation is induced by cooperative interactions which improves the fitness of both biofilm and planktonic populations. We further show that free-living Arthrobacter induces the surface colonization by scavenging the biofilm inhibitor, D-amino acids and receives benefits from the public goods secreted by the biofilm-forming strains. Collectively, our results reveal how cooperative microbial interactions may contribute to microbial coexistence in segregated microhabitats and drive subsurface biofilm community succession.
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