Evidence map›Paper›PMID 37454153›Full record

ReviewNPJ vaccines2023

Maternal and neonatal outcomes of COVID-19 vaccination during pregnancy, a systematic review and meta-analysis.

Greg Marchand, Ahmed Taher Masoud, Sandeep Grover, Alexa King, Giovanna Brazil, Hollie Ulibarri, Julia Parise, Amanda Arroyo, Catherine Coriell, Sydnee Goetz and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in NPJ vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Greg MarchandMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA. gm@marchandinstitute.org.ORCID http://orcid.org/0000-0003-4724-9148
Ahmed Taher MasoudMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Sandeep GroverCenter for Human Genetics, Universitatsklinikum Giessen und Marburg, Marburg, Germany.
Alexa KingMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Giovanna BrazilMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Hollie UlibarriMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Julia PariseMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Amanda ArroyoMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Catherine CoriellMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Sydnee GoetzMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Carmen MoirMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Malini GovindanMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Atley MoberlyMarchand Institute for Minimally Invasive Surgery, Mesa, AZ, USA.
Anna ProctorUniversity of Iowa, College of Public Health, Iowa City, IA, USA.
Katelyn SainzTucson Medical Center, Department of Pediatrics, Tucson, AZ, USA.
Richard BlumrickThe Fetal Diagnostic Center, Mesa, AZ, USA.
Allen Institute · USTucson Medical Center · USUniversitätsklinikum Gießen und Marburg · DEUniversity of Iowa · US

Funding

The Heartland Center for Occupational Health and Safety Education and Research CenterT42OH008491 · OH · UNIVERSITY OF IOWA · PI O'SHAUGHNESSY, PATRICK T · 2005 to 2025
$31.7M
NIOSH CDC HHS T42 OH008491
6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is associated with increased pregnancy complications. Despite effective vaccination strategies for the general population, the evidence on the safety and efficacy of Coronavirus disease 2019 (COVID-19) vaccinations in pregnancy is limited due to a lack of well-powered studies. The present study compares the maternal, neonatal, and immunological outcomes between vaccinated pregnant and unvaccinated pregnant women using a systematic review and meta-analysis approach. We included 37 studies with a total of 141,107 pregnant women (36.8% vaccinated) spread across all outcomes. Our evidence indicates a higher rate of cesarean section in the 1898 vaccinated pregnant women compared to the 6180 women who did not receive vaccination (OR = 1.20, CI = (1.05, 1.38), P = 0.007, I2 = 45%). Regarding immunological outcomes, the risk of SARS-CoV-2 infection during pregnancy or postpartum was significantly reduced in 6820 vaccinated pregnant women compared to 17,010 unvaccinated pregnant women (OR = 0.25, CI = 0.13-0.48, P < 0.0001, I

Identifiers

PMID37454153
PMCPMC10349851
OpenAlexW4384407456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.