ArticleCritical care (London, England)2023
Neighborhood socioeconomic deprivation, healthcare access, and 30-day mortality and readmission after sepsis or critical illness: findings from a nationwide study.
Article in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Contextual nonmedical health factors and critical care-related outcomes: a systematic review.Critical care (London, England) · 2025Pooled it
- Socioeconomic and Regional Disparities in Long-Term Mortality Among Intensive Care Unit Survivors in South Korea: Nationwide Cohort Study.JMIR public health and surveillance · 2026Article
- Scalable extraction of social determinants of health from clinical notes in a sepsis cohort using instruction-tuned language models.JAMIA open · 2026Article
- Association Between Community-Level Social Determinants of Health and Sepsis Incidence and Mortality: A Scoping Review.Critical care explorations · 2026Article
- Pilot implementation and evaluation of a social risk screening tool for hospitalised patients in Singapore.Journal of hospital medicine · 2026Article
- Association of Air Pollution and Socioeconomic Deprivation with Depression and Pain.International journal of environmental research and public health · 2026Article
- The association between different aspects of socioeconomic deprivation and severe maternal morbidity.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Development of the Thailand district-level Socioeconomic Deprivation Index: a census-based methodological study.Health research policy and systems · 2026Article
- Improving representation in critical care research.Intensive care medicine · 2025Article
- Social Precariousness and the Outcome of Critical Illnesses in People with HIV: A Multicenter Cohort Study.Open forum infectious diseases · 2025Article
- A Research Agenda to Mitigate Racial and Ethnic Disparities in U.S. Critical Care Medicine: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Effect of disability, homelessness, and neighborhood marginalization on risk adjustment for hospital performance measurement.American journal of epidemiology · 2025Article
- Associations of Place-Based Factors with Service Use and Consumer-Reported Unmet Service Needs Among Older Adults Using Publicly Funded Home- and Community-Based Services in the United States.International journal of environmental research and public health · 2025Article
- Article
- Review on the Role of Mitochondrial Dysfunction in Septic Encephalopathy.Cell biochemistry and biophysics · 2025Review
- Investigating socioeconomic deprivation and antibiotic prescribing among older medicare patients using an instrumental variable approach.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Polluted Air from Canadian Wildfires and Cardiopulmonary Disease in the Eastern US.JAMA network open · 2024Article
- Area deprivation index, a marker of socioeconomic disadvantage, may predict severity of COVID-19 in patients and which families may experience worse symptoms of PTSD, anxiety, and depression post-ICU.Journal of anesthesia, analgesia and critical care · 2024Article
- Article
- Trajectories of State-Level Sepsis-Related Mortality by Race and Ethnicity Group in the United States.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo determine if neighborhood socioeconomic deprivation independently predicts 30-day mortality and readmission for patients with sepsis or critical illness after adjusting for individual poverty, demographics, comorbidity burden, access to healthcare, and characteristics of treating healthcare facilities.
methodsWe performed a nationwide study of United States Medicare beneficiaries from 2017 to 2019. We identified hospitalized patients with severe sepsis and patients requiring prolonged mechanical ventilation, tracheostomy, or extracorporeal membrane oxygenation (ECMO) through Diagnosis Related Groups (DRGs). We estimated the association between neighborhood socioeconomic deprivation, measured by the Area Deprivation Index (ADI), and 30-day mortality and unplanned readmission using logistic regression models with restricted cubic splines. We sequentially adjusted for demographics, individual poverty, and medical comorbidities, access to healthcare services; and characteristics of treating healthcare facilities.
resultsA total of 1,526,405 admissions were included in the mortality analysis and 1,354,548 were included in the readmission analysis. After full adjustment, 30-day mortality for patients was higher for those from most-deprived neighborhoods (ADI 100) compared to least deprived neighborhoods (ADI 1) for patients with severe sepsis (OR 1.35 95% [CI 1.29-1.42]) or with prolonged mechanical ventilation with or without sepsis (OR 1.42 [95% CI 1.31, 1.54]). This association was linear and dose dependent. However, neighborhood socioeconomic deprivation was not associated with 30-day unplanned readmission for patients with severe sepsis and was inversely associated with readmission for patients requiring prolonged mechanical ventilation with or without sepsis.
conclusionsA strong association between neighborhood socioeconomic deprivation and 30-day mortality for critically ill patients is not explained by differences in individual poverty, demographics, measured baseline medical risk, access to healthcare resources, or characteristics of treating hospitals.
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